Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014-2019

Dinara Galiyeva, Arnur Gusmanov, Yesbolat Sakko, Alpamys Issanov, Kuralay Atageldiyeva, Kainar Kadyrzhanuly, Aiymzhan Nurpeissova, Marzhan Rakhimzhanova, Aigul Durmanova, Antonio Sarria-Santamera, Abduzhappar Gaipov

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

BACKGROUND: We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) and to investigate demographic factors and comorbidities associated with all-cause mortality by aggregating and utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) of Kazakhstan for 2014-2019 years period.

METHODS: A total of 475,539 individuals were included in the analyses. The median years of follow-up for Type 1 DM patients accounted for 4.7 years and 4.5 years in Type 2 DM patients. We used Kaplan-Meier and log-rank test to calculate failure function and differences in survival by age, sex, ethnicity, and comorbidities with all-cause mortality for Type 1 and Type 2 DM. Cox proportional hazards regression analysis was used to obtain crude and adjusted hazard ratios.

RESULTS: Prevalence of Type 1 and Type 2 DM increased 1.7 times from 2014 to 2019. Mortality of Type 1 and Type 2 DM also increased 4 times and 6 times from 2014 to 2019, respectively. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh in patients with Type 1 and Type 2 DM. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death.

CONCLUSION: The prevalence and mortality rate of Type 1 and Type 2 DM increased during the years 2014-2019 in Kazakhstan. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death.

Original languageEnglish
Pages (from-to)275
JournalBMC Endocrine Disorders
Volume22
Issue number1
DOIs
Publication statusPublished - Nov 11 2022

Keywords

  • Female
  • Humans
  • Male
  • Diabetes Mellitus, Type 2/epidemiology
  • Coronary Artery Disease
  • Diabetic Nephropathies
  • Kazakhstan/epidemiology
  • Risk Factors
  • Proportional Hazards Models
  • Stroke
  • Electronics
  • Diabetes Mellitus/epidemiology

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