Abstract
Mathematical modeling for cancerous disease has attracted increasing attention from the researchers around the world. Being an effective tool, it helps to describe the processes that happen to the tumour as the diverse treatment scenarios. In this paper, a density-dependent reaction-diffusion equation is applied to the most aggressive type of brain cancer, Glioblastoma multiforme. The model contains the terms responsible for the growth, migration and proliferation of the malignant tumour. The traveling wave solution used is justified by stability analysis. Numerical simulation of the model is provided and the results are compared with the experimental data obtained from the reference papers.
Original language | English |
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Pages (from-to) | 7234-7247 |
Number of pages | 14 |
Journal | Mathematical Biosciences and Engineering |
Volume | 17 |
Issue number | 6 |
DOIs | |
Publication status | Published - Oct 23 2020 |
Keywords
- Glioblastoma
- Reaction-diffusion equation
- Stability
- Traveling wave solution
- Tumor growth
ASJC Scopus subject areas
- Modelling and Simulation
- General Agricultural and Biological Sciences
- Computational Mathematics
- Applied Mathematics