Abstract
Monkeypox (mpox) is an infectious disease caused by the mpox virus and can
potentially lead to fatal outcomes. It resembles infections caused by viruses from
other families, challenging identification. The pathogenesis, transmission, and
clinical manifestations of mpox and other Orthopoxvirus species are similar due
to their closely related genetic material. This review provides a comprehensive
discussion of the roles of various proteins, including extracellular enveloped virus
(EEV), intracellular mature virus (IMV), and profilin-like proteins of mpox. It also
highlights recent diagnostic techniques based on these proteins to detect this
infection rapidly.
potentially lead to fatal outcomes. It resembles infections caused by viruses from
other families, challenging identification. The pathogenesis, transmission, and
clinical manifestations of mpox and other Orthopoxvirus species are similar due
to their closely related genetic material. This review provides a comprehensive
discussion of the roles of various proteins, including extracellular enveloped virus
(EEV), intracellular mature virus (IMV), and profilin-like proteins of mpox. It also
highlights recent diagnostic techniques based on these proteins to detect this
infection rapidly.
Original language | English |
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Journal | Frontiers in Cellular and Infection Microbiology |
Volume | 14 |
DOIs | |
Publication status | Published - May 28 2024 |