Fabricating sol-gel glass monoliths with controlled nanoporosity

Mohammad Ahmad, Julian R. Jones, Larry L. Hench

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Nanotopography is known to affect cell response, but the mechanisms are unknown. It is therefore important to be able to produce biomaterial surfaces with controllable nanopore sizes and morphologies from materials that can be used to make templates (scaffolds) for tissue regeneration. A rapid method of fabrication of sol-gel monoliths with controlled nanopore size is described in this paper. Pores of 2 nm in diameter were achieved, termed micropores by IUPAC convention. Conventional sol-gel processing yields pores an order of magnitude larger. Gelling time was also reduced from many hours to a few minutes, without using a gelling agent, and large crack-free monoliths were synthesized within 1 week.

Original languageEnglish
Article number002
Pages (from-to)6-10
Number of pages5
JournalBiomedical Materials
Volume2
Issue number1
DOIs
Publication statusPublished - Mar 1 2007

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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