Abstract
In the present study, we report a fabrication of dual-mode carbon coated gadolinia C@Gd2O3 particles by a facile hydrothermal synthesis method without using any organic solvents. The prepared C@Gd2O3 particles have a core-shell structure and a narrow size distribution in the range of 261±27 nm. The fluorescent properties of the prepared C@Gd2O3 particles were accessed by a room-temperature photoluminescence study, while the longitudinal relaxivity (r1) was examined by using a clinical 1.5 T MRI scanner. A murine fibroblast L-929 cell line was used to examine the cytotoxicity and capability of the prepared C@Gd2O3 particles for the fluorescent labeling. The obtained results show that the prepared C@Gd2O3 particles could be used as a dual-mode contrast agent for magnetic resonance and fluorescence imaging.
| Original language | English |
|---|---|
| Pages (from-to) | 118-122 |
| Number of pages | 5 |
| Journal | Journal of Advanced Ceramics |
| Volume | 4 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jun 1 2015 |
| Externally published | Yes |
Fingerprint
Keywords
- carbon
- core-shell structure
- fluorescence
- gadolinia particles
- magnetic resonance imaging (MRI) contrast agent
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
Cite this
Fabrication of carbon coated gadolinia particles for dual-mode magnetic resonance and fluorescence imaging. / Atabaev, Timur Sh; Lee, Jong Ho; Han, Dong Wook; Kim, Hyung Kook; Hwang, Yoon Hwae.
In: Journal of Advanced Ceramics, Vol. 4, No. 2, 01.06.2015, p. 118-122.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fabrication of carbon coated gadolinia particles for dual-mode magnetic resonance and fluorescence imaging
AU - Atabaev, Timur Sh
AU - Lee, Jong Ho
AU - Han, Dong Wook
AU - Kim, Hyung Kook
AU - Hwang, Yoon Hwae
PY - 2015/6/1
Y1 - 2015/6/1
N2 - In the present study, we report a fabrication of dual-mode carbon coated gadolinia C@Gd2O3 particles by a facile hydrothermal synthesis method without using any organic solvents. The prepared C@Gd2O3 particles have a core-shell structure and a narrow size distribution in the range of 261±27 nm. The fluorescent properties of the prepared C@Gd2O3 particles were accessed by a room-temperature photoluminescence study, while the longitudinal relaxivity (r1) was examined by using a clinical 1.5 T MRI scanner. A murine fibroblast L-929 cell line was used to examine the cytotoxicity and capability of the prepared C@Gd2O3 particles for the fluorescent labeling. The obtained results show that the prepared C@Gd2O3 particles could be used as a dual-mode contrast agent for magnetic resonance and fluorescence imaging.
AB - In the present study, we report a fabrication of dual-mode carbon coated gadolinia C@Gd2O3 particles by a facile hydrothermal synthesis method without using any organic solvents. The prepared C@Gd2O3 particles have a core-shell structure and a narrow size distribution in the range of 261±27 nm. The fluorescent properties of the prepared C@Gd2O3 particles were accessed by a room-temperature photoluminescence study, while the longitudinal relaxivity (r1) was examined by using a clinical 1.5 T MRI scanner. A murine fibroblast L-929 cell line was used to examine the cytotoxicity and capability of the prepared C@Gd2O3 particles for the fluorescent labeling. The obtained results show that the prepared C@Gd2O3 particles could be used as a dual-mode contrast agent for magnetic resonance and fluorescence imaging.
KW - carbon
KW - core-shell structure
KW - fluorescence
KW - gadolinia particles
KW - magnetic resonance imaging (MRI) contrast agent
UR - http://www.scopus.com/inward/record.url?scp=84973352435&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84973352435&partnerID=8YFLogxK
U2 - 10.1007/s40145-015-0139-z
DO - 10.1007/s40145-015-0139-z
M3 - Article
VL - 4
SP - 118
EP - 122
JO - Journal of Advanced Ceramics
JF - Journal of Advanced Ceramics
SN - 2226-4108
IS - 2
ER -