Abstract
In the present study, we report a fabrication of dual-mode carbon coated gadolinia C@Gd2O3 particles by a facile hydrothermal synthesis method without using any organic solvents. The prepared C@Gd2O3 particles have a core-shell structure and a narrow size distribution in the range of 261±27 nm. The fluorescent properties of the prepared C@Gd2O3 particles were accessed by a room-temperature photoluminescence study, while the longitudinal relaxivity (r1) was examined by using a clinical 1.5 T MRI scanner. A murine fibroblast L-929 cell line was used to examine the cytotoxicity and capability of the prepared C@Gd2O3 particles for the fluorescent labeling. The obtained results show that the prepared C@Gd2O3 particles could be used as a dual-mode contrast agent for magnetic resonance and fluorescence imaging.
Original language | English |
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Pages (from-to) | 118-122 |
Number of pages | 5 |
Journal | Journal of Advanced Ceramics |
Volume | 4 |
Issue number | 2 |
DOIs | |
Publication status | Published - Jun 1 2015 |
Externally published | Yes |
Keywords
- carbon
- core-shell structure
- fluorescence
- gadolinia particles
- magnetic resonance imaging (MRI) contrast agent
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites