Fiber-optic technologies for advanced thermo-Therapy applied ex vivo to liver tumors

D. Tosi, G. Perrone, A. Vallan, A. Braglia, Y. Liu, E. G. Macchi, G. Braschi, M. Gallati, A. Cigada, S. Poeggel, D. B. Duraibabu, G. Leen, E. Lewis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)


Thermal ablation, using radiofrequency, microwave, and laser sources, is a common treatment for hepatic tumors. Sensors allow monitoring, at the point of treatment, the evolution of thermal ablation procedures. We present optical fiber sensors that allow advanced capabilities for recording the biophysical phenomena occurring in the tissue in real time. Distributed or quasi-distributed thermal sensors allow recording temperature with spatial resolution ranging from 0.1 mm to 5 mm. In addition, a thermally insensitive pressure sensor allows recording pressure rise, supporting advanced treatment of encapsulated tumors. Our investigation is focused on two case studies: (1) radiofrequency ablation of hepatic tissue, performed on a phantom with a stem-shaped applicator; (2) laser ablation of a liver phantom, performed with a fiber laser. The main measurement results are discussed, comparing the technologies used for the investigation, and drawing the potential for using optical fiber sensors for "smart"-Ablation.

Original languageEnglish
Title of host publicationClinical and Biomedical Spectroscopy and Imaging IV
EditorsJ. Quincy Brown, Volker Deckert
ISBN (Electronic)9781628417029
Publication statusPublished - Jan 1 2015
EventClinical and Biomedical Spectroscopy and Imaging IV - Munich, Germany
Duration: Jun 22 2015Jun 24 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceClinical and Biomedical Spectroscopy and Imaging IV


  • Optical fiber sensors (OFS)
  • interventional cancer care
  • liver tumor ablation
  • thermal ablation
  • thermo-Therapy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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