Abstract
We present a software package for fast pedigree reconstruction in natural populations using co-dominant genomic markers such as microsatellites and SNPs. If available, the algorithm makes use of prior information such as known relationships (sub-pedigrees) or the age and sex of individuals. Statistical confidence is estimated by a simulation of the sampling process. The accuracy of the algorithm is demonstrated for simulated data as well as an empirical data set with known pedigree. The parentage inference is robust even in the presence of genotyping errors.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the German Conference on Bioinformatics, GCB 2008 |
| Pages | 168-177 |
| Number of pages | 10 |
| Publication status | Published - Dec 1 2008 |
| Event | German Conference on Bioinformatics, GCB 2008 - Dresden, Germany Duration: Sep 9 2008 → Sep 12 2008 |
Publication series
| Name | Proceedings of the German Conference on Bioinformatics, GCB 2008 |
|---|
Other
| Other | German Conference on Bioinformatics, GCB 2008 |
|---|---|
| Country | Germany |
| City | Dresden |
| Period | 9/9/08 → 9/12/08 |
Fingerprint
ASJC Scopus subject areas
- Information Systems
- Biomedical Engineering
Cite this
Riester, M., Stadler, P. F., & Klemm, K. (2008). FRANz: Fast reconstruction of wild pedigrees. In Proceedings of the German Conference on Bioinformatics, GCB 2008 (pp. 168-177). (Proceedings of the German Conference on Bioinformatics, GCB 2008).