Genetics - Cellular basis

Andrea Buda, Massimo Pignatelli

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Colorectal carcinogenesis is a multistep process during which the specialised epithelial cells of intestinal mucosa surface (e.g. colonocytes) accumulate a series of genetic and epigenetic events which lead to a perturbation of their normal cellular functions and turnover. This review will address the mechanisms and biological effects of these abnormalities on the growth control, differentiation, adhesion and survival of the colonocytes.

Original languageEnglish
Pages (from-to)45-58
Number of pages14
JournalBritish Medical Bulletin
Volume64
DOIs
Publication statusPublished - 2002
Externally publishedYes

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Intestinal Mucosa
Epigenomics
Carcinogenesis
Epithelial Cells
Growth

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Genetics - Cellular basis. / Buda, Andrea; Pignatelli, Massimo.

In: British Medical Bulletin, Vol. 64, 2002, p. 45-58.

Research output: Contribution to journalArticle

Buda, Andrea ; Pignatelli, Massimo. / Genetics - Cellular basis. In: British Medical Bulletin. 2002 ; Vol. 64. pp. 45-58.
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