Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019

Sara Momtazmanesh, Sahar Saeedi Moghaddam, Seyyed-Hadi Ghamari, Elaheh Malakan Rad, Negar Rezaei, Parnian Shobeiri, Amirali Aali, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Michael Abdelmasseh, Meriem Abdoun, Deldar Morad Abdulah, Abu Yousuf Md Abdullah, Aidin Abedi, Hassan Abolhassani, Zahra Abrehdari-Tafreshi, Basavaprabhu Achappa, Denberu Eshetie Adane Adane, Tigist Demssew Adane, Isaac Yeboah AddoMohammad Adnan, Qorinah Estiningtyas Sakilah Adnani, Sajjad Ahmad, Ali Ahmadi, Keivan Ahmadi, Ali Ahmed, Ayman Ahmed, Tarik Ahmed Rashid, Hanadi Al Hamad, Fares Alahdab, Astawus Alemayehu, Sheikh Mohammad Alif, Syed Mohamed Aljunid, Sami Almustanyir, Khalid A. Altirkawi, Nelson Alvis-Guzman, Javad Aminian Dehkordi, Mehrdad Amir-Behghadami, Robert Ancuceanu, Catalina Liliana Andrei, Tudorel Andrei, Catherine M. Antony, Anayochukwu Edward Anyasodor, Jalal Arabloo, Judie Arulappan, Tahira Ashraf, Seyyed Shamsadin Athari, Engi F. Attia, Meshesha Tsegazeab Ayele, Sina Azadnajafabad, Abraham Samuel Babu, Sara Bagherieh, Ovidiu Constantin Baltatu, Maciej Banach, Mainak Bardhan, Francesco Barone-Adesi, Amadou Barrow, Saurav Basu, Nebiyou Simegnew Bayileyegn, Isabela M. Bensenor, Nikha Bhardwaj, Pankaj Bhardwaj, Ajay Nagesh Bhat, Krittika Bhattacharyya, Souad Bouaoud, Dejana Braithwaite, Michael Brauer, Muhammad Hammad Butt, Zahid A. Butt, Daniela Calina, Luis Alberto Cámera, Gashaw Sisay Chanie, Periklis Charalampous, Vijay Kumar Chattu, Odgerel Chimed-Ochir, Dinh-Toi Chu, Aaron J. Cohen, Natália Cruz-Martins, Omid Dadras, Aso Mohammad Darwesh, Saswati Das, Sisay Abebe Debela, Laura Delgado-Ortiz, Diriba Dereje, Mostafa Dianatinasab, Nancy Diao, Daniel Diaz, Lankamo Ena Digesa, Gebisa Dirirsa, Paul Narh Doku, Deepa Dongarwar, Abdel Douiri, Haneil Larson Dsouza, Ebrahim Eini, Michael Ekholuenetale, Temitope Cyrus Ekundayo, Ahmed Elabbas Mustafa Elagali, Muhammed Elhadi, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Farshid Etaee, Adeniyi Francis Fagbamigbe, Andre Faro, Ali Fatehizadeh, Ginenus Fekadu, Irina Filip, Florian Fischer, Masoud Foroutan, Richard Charles Franklin, Peter Andras Gaal, Santosh Gaihre, Abduzhappar Gaipov, Mesfin Gebrehiwot, Urge Gerema, Motuma Erena Getachew, Tamiru Getachew, Mansour Ghafourifard, Reza Ghanbari, Ahmad Ghashghaee, Ali Gholami, Artyom Urievich Gil, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Habtamu Alganeh Guadie, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Mostafa Hadei, Rabih Halwani, Asif Hanif, Arief Hargono, Mehdi Harorani, Risky Kusuma Hartono, Hamidreza Hasani, Abdiwahab Hashi, Simon I. Hay, Mohammad Heidari, Merel E. Hellemons, Claudiu Herteliu, Ramesh Holla, Nobuyuki Horita, Mohammad Hoseini, Mehdi Hosseinzadeh, Junjie Huang, Salman Hussain, Bing-Fang Hwang, Ivo Iavicoli, Segun Emmanuel Ibitoye, Sufyan Ibrahim, Olayinka Stephen Ilesanmi, Irena M. Ilic, Milena D. Ilic, Mustapha Immurana, Nahlah Elkudssiah Ismail, Linda Merin J, Mihajlo Jakovljevic, Elham Jamshidi, Manthan Dilipkumar Janodia, Tahereh Javaheri, Sathish Kumar Jayapal, Shubha Jayaram, Ravi Prakash Jha, Olatunji Johnson, Tamas Joo, Nitin Joseph, Jacek Jerzy Jozwiak, Vaishali K, Billingsley Kaambwa, Zubair Kabir, Laleh R. Kalankesh, Rohollah Kalhor, Himal Kandel, Shama D. Karanth, Ibraheem M. Karaye, Bekalu Getnet Kassa, Gizat M. Kassie, Leila Keikavoosi-Arani, Mohammad Keykhaei, Himanshu Khajuria, Imteyaz A. Khan, Moien A.B. Khan, Yusra H. Khan, Haneen Khreis, Min Seo Kim, Adnan Kisa, Sezer Kisa, Luke D. Knibbs, Pavel Kolkhir, Somayeh Komaki, Farzad Kompani, Hamid Reza Koohestani, Ali Koolivand, Oleksii Korzh, Ai Koyanagi, Kewal Krishan, Kris J. Krohn, Naveen Kumar, Nithin Kumar, Om P. Kurmi, Ambily Kuttikkattu, Carlo La Vecchia, Judit Lám, Qing Lan, Savita Lasrado, Kamaluddin Latief, Paolo Lauriola, Sang-woong Lee, Yo Han Lee, Samson Mideksa Legesse, Jacopo Lenzi, Ming-Chieh Li, Ro-Ting Lin, Gang Liu, Wei Liu, Chun-Han Lo, László Lorenzovici, Yifei Lu, Soundarya Mahalingam, Elham Mahmoudi, Narayan B. Mahotra, Mohammad-Reza Malekpour, Ahmad Azam Malik, Tauqeer Hussain Mallhi, Deborah Carvalho Malta, Borhan Mansouri, Elezebeth Mathews, Sazan Qadir Maulud, Enkeleint A. Mechili, Entezar Mehrabi Nasab, Ritesh G. Menezes, Dechasa Adare Mengistu, Alexios-Fotios Mentis, Mahboobeh Meshkat, Tomislav Mestrovic, Ana Carolina Micheletti Gomide Nogueira de Sá, Erkin M. Mirrakhimov, Awoke Misganaw, Prasanna Mithra, Javad Moghadasi, Esmaeil Mohammadi, Mokhtar Mohammadi, Marita Mohammadshahi, Shafiu Mohammed, Syam Mohan, Nagabhishek Moka, Lorenzo Monasta, Mohammad Ali Moni, Md Moniruzzaman, Fateme Montazeri, Maryam Moradi, Ebrahim Mostafavi, Christine Mpundu-Kaambwa, Efrén Murillo-Zamora, Christopher J.L. Murray, Tapas Sadasivan Nair, Vinay Nangia, Sreenivas Narasimha Swamy, Aparna Ichalangod Narayana, Zuhair S. Natto, Biswa Prakash Nayak, Wogene Wogene Negash, Evangelia Nena, Sandhya Neupane Kandel, Robina Khan Niazi, Antonio Tolentino Nogueira de Sá, Ali Nowroozi, Chimezie Igwegbe Nzoputam, Ogochukwu Janet Nzoputam, Bogdan Oancea, Rahman Md Obaidur, Oluwakemi Ololade Odukoya, Hassan Okati-Aliabad, Akinkunmi Paul Okekunle, Osaretin Christabel Okonji, Andrew T. Olagunju, Ahmed Omar Bali, Sergej M. Ostojic, Mahesh P. A, Alicia Padron-Monedero, Jagadish Rao Padubidri, Mohammad Taha Pahlevan Fallahy, Tamás Palicz, Adrian Pana, Eun-Kee Park, Jay Patel, Rajan Paudel, Uttam Paudel, Paolo Pedersini, Marcos Pereira, Renato B. Pereira, Ionela-Roxana Petcu, Majid Pirestani, Maarten J. Postma, Akila Prashant, Mohammad Rabiee, Amir Radfar, Sima Rafiei, Fakher Rahim, Mohammad Hifz Ur Rahman, Mosiur Rahman, Muhammad Aziz Rahman, Amir Masoud Rahmani, Shayan Rahmani, Vahid Rahmanian, Prashant Rajput, Juwel Rana, Chythra R. Rao, Sowmya J. Rao, Sina Rashedi, Mohammad-Mahdi Rashidi, Zubair Ahmed Ratan, David Laith Rawaf, Salman Rawaf, Lal Rawal, Reza Rawassizadeh, Mohammad Sadegh Razeghinia, Elrashdy Moustafa Mohamed Redwan, Maryam Rezaei, Nazila Rezaei, Nima Rezaei, Mohsen Rezaeian, Mónica Rodrigues, Jefferson Antonio Buendia Rodriguez, Leonardo Roever, David Rojas-Rueda, Kristina E. Rudd, Aly M.A. Saad, Siamak Sabour, Basema Saddik, Erfan Sadeghi, Masoumeh Sadeghi, Umar Saeed, Maryam Sahebazzamani, Amirhossein Sahebkar, Harihar Sahoo, Mirza Rizwan Sajid, Sateesh Sakhamuri, Sana Salehi, Abdallah M. Samy, Milena M. Santric-Milicevic, Bruno Piassi Sao Jose, Brijesh Sathian, Maheswar Satpathy, Ganesh Kumar Saya, Subramanian Senthilkumaran, Allen Seylani, Saeed Shahabi, Masood Ali Shaikh, Mohd Shanawaz, Mohammed Shannawaz, Rahim Ali Sheikhi, Shashank Shekhar, Migbar Mekonnen Sibhat, Colin R. Simpson, Jasvinder A. Singh, Paramdeep Singh, Surjit Singh, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Mohammad Sadegh Soltani-Zangbar, Suhang Song, Ireneous N. Soyiri, Paschalis Steiropoulos, Leo Stockfelt, Jing Sun, Ken Takahashi, Iman M. Talaat, Ker-Kan Tan, Nathan Y. Tat, Vivian Y. Tat, Birhan Tsegaw Taye, Pugazhenthan Thangaraju, Rekha Thapar, Friedrich Thienemann, Amir Tiyuri, Mai Thi Ngoc Tran, Jaya Prasad Tripathy, Lorainne Tudor Car, Biruk Shalmeno Tusa, Irfan Ullah, Sana Ullah, Marco Vacante, Pascual R. Valdez, Rohollah Valizadeh, Job F.M. van Boven, Tommi Juhani Vasankari, Siavash Vaziri, Francesco S. Violante, Bay Vo, Ning Wang, Melissa Y. Wei, Ronny Westerman, Nuwan Darshana Wickramasinghe, Suowen Xu, Xiaoyue Xu, Lalit Yadav, Yazachew Yismaw, Dong Keon Yon, Naohiro Yonemoto, Chuanhua Yu, Yong Yu, Ismaeel Yunusa, Mazyar Zahir, Moein Zangiabadian, Zahra Zareshahrabadi, Armin Zarrintan, Mikhail Sergeevich Zastrozhin, Zelalem Banjaw Zegeye, Yunquan Zhang, Mohsen Naghavi, Bagher Larijani, Farshad Farzadfar

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Background
Updated data on chronic respiratory diseases (CRDs) are vital in their prevention, control, and treatment in the path to achieving the third UN Sustainable Development Goals (SDGs), a one-third reduction in premature mortality from non-communicable diseases by 2030. We provided global, regional, and national estimates of the burden of CRDs and their attributable risks from 1990 to 2019.
Methods
Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we estimated mortality, years lived with disability, years of life lost, disability-adjusted life years (DALYs), prevalence, and incidence of CRDs, i.e. chronic obstructive pulmonary disease (COPD), asthma, pneumoconiosis, interstitial lung disease and pulmonary sarcoidosis, and other CRDs, from 1990 to 2019 by sex, age, region, and Socio-demographic Index (SDI) in 204 countries and territories. Deaths and DALYs from CRDs attributable to each risk factor were estimated according to relative risks, risk exposure, and the theoretical minimum risk exposure level input.
Findings
In 2019, CRDs were the third leading cause of death responsible for 4.0 million deaths (95% uncertainty interval 3.6–4.3) with a prevalence of 454.6 million cases (417.4–499.1) globally. While the total deaths and prevalence of CRDs have increased by 28.5% and 39.8%, the age-standardised rates have dropped by 41.7% and 16.9% from 1990 to 2019, respectively. COPD, with 212.3 million (200.4–225.1) prevalent cases, was the primary cause of deaths from CRDs, accounting for 3.3 million (2.9–3.6) deaths. With 262.4 million (224.1–309.5) prevalent cases, asthma had the highest prevalence among CRDs. The age-standardised rates of all burden measures of COPD, asthma, and pneumoconiosis have reduced globally from 1990 to 2019. Nevertheless, the age-standardised rates of incidence and prevalence of interstitial lung disease and pulmonary sarcoidosis have increased throughout this period. Low- and low-middle SDI countries had the highest age-standardised death and DALYs rates while the high SDI quintile had the highest prevalence rate of CRDs. The highest deaths and DALYs from CRDs were attributed to smoking globally, followed by air pollution and occupational risks. Non-optimal temperature and high body-mass index were additional risk factors for COPD and asthma, respectively.
Interpretation
Albeit the age-standardised prevalence, death, and DALYs rates of CRDs have decreased, they still cause a substantial burden and deaths worldwide. The high death and DALYs rates in low and low-middle SDI countries highlights the urgent need for improved preventive, diagnostic, and therapeutic measures. Global strategies for tobacco control, enhancing air quality, reducing occupational hazards, and fostering clean cooking fuels are crucial steps in reducing the burden of CRDs, especially in low- and lower-middle income countries.
Original languageEnglish
JournalEClinicalMedicine
DOIs
Publication statusPublished - Apr 27 2023

Fingerprint

Dive into the research topics of 'Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019'. Together they form a unique fingerprint.

Cite this