Dinamika urovnia glutationa i aktivnosti fermentov obmena glutationa v éritrotsitakh bol'nykh ostrym kholetsistitom.

Translated title of the contribution: Glutathione levels and the activity of the enzymes of glutathione metabolism in erythrocytes of patients with acute cholecystitis

V. S. Pomelov, Z. S. Zhumalilov, R. N. Korotkina, A. A. Karelin

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

It is shown that in acute cholecystitis patients versus chronic cholecystitis ones and donors, the total glutathione in blood is lower while the activity of glutathione metabolism enzymes in red blood cells inhibited. Enzymological findings correlate with clinical symptoms of intoxication. Surgery aggravates disturbed activity of the enzymes. Conventional conservative therapy is not effective in normalizing the enzymes activity either. A good therapeutic response can be achieved by a directed transport of antibiotics in autologous blood ghosts which promotes recovery of normal activity of glutathione metabolism enzymes, routine glutathione level, early stabilization of hepatocytic membranes beneficial for surgical patients.

Original languageRussian
Pages (from-to)27-30
Number of pages4
JournalSovetskaya Meditsina
Issue number8
Publication statusPublished - 1991
Externally publishedYes

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Acute Cholecystitis
Glutathione
Erythrocytes
Enzymes
Cholecystitis
Tissue Donors
Anti-Bacterial Agents
Membranes
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dinamika urovnia glutationa i aktivnosti fermentov obmena glutationa v éritrotsitakh bol'nykh ostrym kholetsistitom. / Pomelov, V. S.; Zhumalilov, Z. S.; Korotkina, R. N.; Karelin, A. A.

In: Sovetskaya Meditsina, No. 8, 1991, p. 27-30.

Research output: Contribution to journalArticle

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