The parathyroid hormone (PTH) is important for the calcium balance in humans. It apparently participates in the development of osteoporosis, especially in the senile type (Type II). This study investigates the parathyroid hormone inhibitory bioactivity of the human fetal and neonatal thymus. The PTH inhibiting bioactivity was determined in the human fetal and neonatal thymus glands specimen (HTE - human fetal thymus extract) obtained in post mortem autopsies immediately after spontaneous abortion or delivery. PTH was evaluated by quantitative bioassay on experimental animals (36 rats) after the administration of HTE and PTH standard (Bachem). The obtained data suggest thatt the thymic gland possesses an antiparathyroid inhibitory bioactivity.
|Number of pages||4|
|Journal||International Journal of Thymology|
|Publication status||Published - Dec 1 1995|
- antiparathyroid effect
- parathyroid hormone
ASJC Scopus subject areas