Impact of conception method on twin pregnancy course and outcome

S. Andrijasevic, J. Dotlic, S. Aksam, J. Micic, M. Terzic

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: The aim of the study was to investigate the course and outcomes of twin pregnancies conceived by different methods of assisted reproduction (ART) compared to those conceived spontaneously. Methods: The study involved patients with twin pregnancies who delivered at the Ob/Gyn Clinic of the Clinical Center of Serbia over a period of three years. Patients were differentiated according to method of conception and type of ART. Age, parity, etiology of infertility, pregnancy complications, time of membrane rupture and type of delivery was recorded for each patient. Gestational week at delivery, presentation, birth weight, Apgar score, chorionicity and accompanying disorders were separately recorded for each twin. The data were analyzed statistically. Results: A total of 431 patients were included in the study. Although more twins were conceived by ART, the difference was not statistically significant (p = 0.092). The most common ART procedure was IVF/ICSI (p = 0.001). ART procedures, particularly IVF/ICSI, were significantly correlated with more advanced maternal age, fewer previous pregnancies and delivery by cesarean sections, usually planned (p = 0.001). Preterm membrane rupture was more common after ICSI, but preterm delivery and pregnancy complications were infrequent, irrespective of the method of conception (p = 0.001). ART twins were mostly dichorionic (p = 0.036). Monochorionic twins were conceived either spontaneously or with ICSI. Conception by ART was not correlated with twins' outcome (weight, Apgar score, disorders). Conclusions: ART procedures do not have a negative impact on twin pregnancy course and outcome. Twin pregnancies conceived spontaneously or by ART have similar outcomes.

Original languageEnglish
Pages (from-to)933-939
Number of pages7
JournalGeburtshilfe und Frauenheilkunde
Volume74
Issue number10
DOIs
Publication statusPublished - Jan 1 2014
Externally publishedYes

Fingerprint

Twin Pregnancy
Pregnancy Outcome
Reproduction
Intracytoplasmic Sperm Injections
Apgar Score
Pregnancy Complications
Rupture
Serbia
Membranes
Maternal Age
Parity
Birth Weight
Cesarean Section
Infertility
Weights and Measures
Pregnancy

Keywords

  • assisted reproductive technology (ART)
  • pregnancy
  • pregnancy outcome
  • spontaneous conception
  • twins

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Maternity and Midwifery

Cite this

Impact of conception method on twin pregnancy course and outcome. / Andrijasevic, S.; Dotlic, J.; Aksam, S.; Micic, J.; Terzic, M.

In: Geburtshilfe und Frauenheilkunde, Vol. 74, No. 10, 01.01.2014, p. 933-939.

Research output: Contribution to journalArticle

Andrijasevic, S. ; Dotlic, J. ; Aksam, S. ; Micic, J. ; Terzic, M. / Impact of conception method on twin pregnancy course and outcome. In: Geburtshilfe und Frauenheilkunde. 2014 ; Vol. 74, No. 10. pp. 933-939.
@article{4f70fe2a2cb443fdb700c78545c99cf8,
title = "Impact of conception method on twin pregnancy course and outcome",
abstract = "Objective: The aim of the study was to investigate the course and outcomes of twin pregnancies conceived by different methods of assisted reproduction (ART) compared to those conceived spontaneously. Methods: The study involved patients with twin pregnancies who delivered at the Ob/Gyn Clinic of the Clinical Center of Serbia over a period of three years. Patients were differentiated according to method of conception and type of ART. Age, parity, etiology of infertility, pregnancy complications, time of membrane rupture and type of delivery was recorded for each patient. Gestational week at delivery, presentation, birth weight, Apgar score, chorionicity and accompanying disorders were separately recorded for each twin. The data were analyzed statistically. Results: A total of 431 patients were included in the study. Although more twins were conceived by ART, the difference was not statistically significant (p = 0.092). The most common ART procedure was IVF/ICSI (p = 0.001). ART procedures, particularly IVF/ICSI, were significantly correlated with more advanced maternal age, fewer previous pregnancies and delivery by cesarean sections, usually planned (p = 0.001). Preterm membrane rupture was more common after ICSI, but preterm delivery and pregnancy complications were infrequent, irrespective of the method of conception (p = 0.001). ART twins were mostly dichorionic (p = 0.036). Monochorionic twins were conceived either spontaneously or with ICSI. Conception by ART was not correlated with twins' outcome (weight, Apgar score, disorders). Conclusions: ART procedures do not have a negative impact on twin pregnancy course and outcome. Twin pregnancies conceived spontaneously or by ART have similar outcomes.",
keywords = "assisted reproductive technology (ART), pregnancy, pregnancy outcome, spontaneous conception, twins",
author = "S. Andrijasevic and J. Dotlic and S. Aksam and J. Micic and M. Terzic",
year = "2014",
month = "1",
day = "1",
doi = "10.1055/s-0034-1383148",
language = "English",
volume = "74",
pages = "933--939",
journal = "Geburtshilfe und Frauenheilkunde",
issn = "0016-5751",
publisher = "Georg Thieme Verlag",
number = "10",

}

TY - JOUR

T1 - Impact of conception method on twin pregnancy course and outcome

AU - Andrijasevic, S.

AU - Dotlic, J.

AU - Aksam, S.

AU - Micic, J.

AU - Terzic, M.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Objective: The aim of the study was to investigate the course and outcomes of twin pregnancies conceived by different methods of assisted reproduction (ART) compared to those conceived spontaneously. Methods: The study involved patients with twin pregnancies who delivered at the Ob/Gyn Clinic of the Clinical Center of Serbia over a period of three years. Patients were differentiated according to method of conception and type of ART. Age, parity, etiology of infertility, pregnancy complications, time of membrane rupture and type of delivery was recorded for each patient. Gestational week at delivery, presentation, birth weight, Apgar score, chorionicity and accompanying disorders were separately recorded for each twin. The data were analyzed statistically. Results: A total of 431 patients were included in the study. Although more twins were conceived by ART, the difference was not statistically significant (p = 0.092). The most common ART procedure was IVF/ICSI (p = 0.001). ART procedures, particularly IVF/ICSI, were significantly correlated with more advanced maternal age, fewer previous pregnancies and delivery by cesarean sections, usually planned (p = 0.001). Preterm membrane rupture was more common after ICSI, but preterm delivery and pregnancy complications were infrequent, irrespective of the method of conception (p = 0.001). ART twins were mostly dichorionic (p = 0.036). Monochorionic twins were conceived either spontaneously or with ICSI. Conception by ART was not correlated with twins' outcome (weight, Apgar score, disorders). Conclusions: ART procedures do not have a negative impact on twin pregnancy course and outcome. Twin pregnancies conceived spontaneously or by ART have similar outcomes.

AB - Objective: The aim of the study was to investigate the course and outcomes of twin pregnancies conceived by different methods of assisted reproduction (ART) compared to those conceived spontaneously. Methods: The study involved patients with twin pregnancies who delivered at the Ob/Gyn Clinic of the Clinical Center of Serbia over a period of three years. Patients were differentiated according to method of conception and type of ART. Age, parity, etiology of infertility, pregnancy complications, time of membrane rupture and type of delivery was recorded for each patient. Gestational week at delivery, presentation, birth weight, Apgar score, chorionicity and accompanying disorders were separately recorded for each twin. The data were analyzed statistically. Results: A total of 431 patients were included in the study. Although more twins were conceived by ART, the difference was not statistically significant (p = 0.092). The most common ART procedure was IVF/ICSI (p = 0.001). ART procedures, particularly IVF/ICSI, were significantly correlated with more advanced maternal age, fewer previous pregnancies and delivery by cesarean sections, usually planned (p = 0.001). Preterm membrane rupture was more common after ICSI, but preterm delivery and pregnancy complications were infrequent, irrespective of the method of conception (p = 0.001). ART twins were mostly dichorionic (p = 0.036). Monochorionic twins were conceived either spontaneously or with ICSI. Conception by ART was not correlated with twins' outcome (weight, Apgar score, disorders). Conclusions: ART procedures do not have a negative impact on twin pregnancy course and outcome. Twin pregnancies conceived spontaneously or by ART have similar outcomes.

KW - assisted reproductive technology (ART)

KW - pregnancy

KW - pregnancy outcome

KW - spontaneous conception

KW - twins

UR - http://www.scopus.com/inward/record.url?scp=84911922961&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84911922961&partnerID=8YFLogxK

U2 - 10.1055/s-0034-1383148

DO - 10.1055/s-0034-1383148

M3 - Article

VL - 74

SP - 933

EP - 939

JO - Geburtshilfe und Frauenheilkunde

JF - Geburtshilfe und Frauenheilkunde

SN - 0016-5751

IS - 10

ER -