TY - JOUR
T1 - Impact of lifestyle and diet on endometriosis
T2 - a fresh look to a busy corner
AU - Habib, Nassir
AU - Buzzaccarini, Giovanni
AU - Centini, Gabriele
AU - Moawad, Gaby N.
AU - Ceccaldi, Pierre Francois
AU - Gitas, Georgios
AU - Alkatout, Ibrahim
AU - Gullo, Giuseppe
AU - Terzic, Sanja
AU - Sleiman, Zaki
N1 - Publisher Copyright:
© 2022 Termedia Publishing House Ltd.. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Endometriosis is a chronic inflammatory disorder with a prevalence of six to ten percent in women of childbearing age. As long as the aetiology of endometriosis is not fully understood and the disease has no definitive treatment, an examination of the environmental factors or interventions that could modify or cure endometriosis would greatly benefit women suffering from this chronic condition. This literature review utilized the electronic databases PubMed, EMBASE, and MEDLINE until February 2021. Studies indicate that fish oil may have a positive effect on reducing endometriosis-related pain due to the effects of pro-inflammatory prostaglandins derived from omega-3 fatty acids. The same effect was seen with the introduction of antioxidant vitamins C, D, and E. There is clinical viability of a low fermentable oligo-, di-, and monosaccharides and polyols diet to successfully reduce the symptoms of patients who suffer from both endometriosis and irritable bowel syndrome. Despite the low level of evidence, there are frequent associations between endometriosis and gastrointestinal conditions in addition to the influence of various nutritional factors on the disease. The management of endometriosis requires a holistic approach focused on reducing overall inflammation, increasing detoxification, and attenuating troublesome symptoms. A dietician may provide great benefit in the management of these patients, especially at younger ages and in early stages. High-level evidence and welldesigned randomized studies are lacking when it comes to studying the effect of lifestyle and dietary intake on endometriosis. Inarguably, further research with a more extensive focus is needed.
AB - Endometriosis is a chronic inflammatory disorder with a prevalence of six to ten percent in women of childbearing age. As long as the aetiology of endometriosis is not fully understood and the disease has no definitive treatment, an examination of the environmental factors or interventions that could modify or cure endometriosis would greatly benefit women suffering from this chronic condition. This literature review utilized the electronic databases PubMed, EMBASE, and MEDLINE until February 2021. Studies indicate that fish oil may have a positive effect on reducing endometriosis-related pain due to the effects of pro-inflammatory prostaglandins derived from omega-3 fatty acids. The same effect was seen with the introduction of antioxidant vitamins C, D, and E. There is clinical viability of a low fermentable oligo-, di-, and monosaccharides and polyols diet to successfully reduce the symptoms of patients who suffer from both endometriosis and irritable bowel syndrome. Despite the low level of evidence, there are frequent associations between endometriosis and gastrointestinal conditions in addition to the influence of various nutritional factors on the disease. The management of endometriosis requires a holistic approach focused on reducing overall inflammation, increasing detoxification, and attenuating troublesome symptoms. A dietician may provide great benefit in the management of these patients, especially at younger ages and in early stages. High-level evidence and welldesigned randomized studies are lacking when it comes to studying the effect of lifestyle and dietary intake on endometriosis. Inarguably, further research with a more extensive focus is needed.
KW - chronic pelvic pain
KW - diet
KW - endometriosis
KW - lifestyle
KW - nutrition
UR - http://www.scopus.com/inward/record.url?scp=85133486158&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85133486158&partnerID=8YFLogxK
U2 - 10.5114/pm.2022.116437
DO - 10.5114/pm.2022.116437
M3 - Review article
AN - SCOPUS:85133486158
SN - 1643-8876
VL - 21
SP - 124
EP - 132
JO - Przeglad Menopauzalny
JF - Przeglad Menopauzalny
IS - 2
ER -