Incidence and mortality rates of strokes in Kazakhstan in 2014-2019

Gulnur Zhakhina, Bakhytbek Zhalmagambetov, Arnur Gusmanov, Yesbolat Sakko, Sauran Yerdessov, Elzar Matmusaeva, Aliya Imanova, Byron Crape, Antonio Sarria-Santamera, Abduzhappar Gaipov

Research output: Contribution to journalArticlepeer-review


There is a lack of information on the epidemiology of acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) in developing countries. This research presents incidence and mortality rates of stroke patients based on hospital admission and discharge status in one of the Central Asian countries by analysis of large-scale healthcare data. The registry data of 177,947 patients admitted to the hospital with the diagnosis of stroke between 2014 and 2019 were extracted from the National Electronic Health System of Kazakhstan. We provide descriptive statistics and analyze the association of socio-demographic and medical characteristics such as comorbidities and surgical treatments. Among all stroke patients, the incidence rate based on hospital admission of AIS was significantly higher compared to SAH and ICH patients. In 5 year follow-up period, AIS patients had a better outcome than SAH and ICH patients (64.7, 63.1 and 57.3% respectively). The hazard ratio (HR) after the trepanation and decompression surgery was 2.3 and 1.48 for AIS and SAH patients; however, it was protective for ICH (HR = 0.87). The investigation evaluated an increase in the all-cause mortality rates based on the discharge status of stroke patients, while the incidence rate decreased over time.

Original languageEnglish
Pages (from-to)16041
JournalScientific Reports
Issue number1
Publication statusPublished - Sept 26 2022


  • Cerebral Hemorrhage/diagnosis
  • Humans
  • Incidence
  • Ischemic Stroke
  • Kazakhstan/epidemiology
  • Stroke/diagnosis
  • Subarachnoid Hemorrhage


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