Influence of waveform on cell viability during ultrasound exposure

Timur Saliev, Loreto B. Feril, Donald A. McLean, Katsuro Tachibana, Paul A. Campbell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We examined the role of ultrasound standing waves, and their travelling wave counterparts, on cell viability in an in-vitro insonation apparatus. Furthermore, the effect of distinct waveforms (sine and top-hat) was also explored, together with the role of microbubble presence. Measurements of cell viability in standing wave scenarios demonstrated a relatively higher rate of lysis (63.13 ± 10.89% remaining viable) compared with the travelling wave data, where 96.22 ± 4.0% remained viable. Significant differences were also seen as a function of waveform, where insonations employing top-hat wave shapes resulted in an average end stage viability of 30.31 ± 5.71 % compared with 61.94 ± 14.28 % in the sinusoidal counterparts.

Original languageEnglish
Title of host publicationAIP Conference Proceedings
Pages367-370
Number of pages4
Volume1359
DOIs
Publication statusPublished - 2011
Externally publishedYes
Event10th International Symposium on Therapeutic Ultrasound, ISTU 2010 - Tokyo, Japan
Duration: Jun 9 2010Jun 12 2010

Other

Other10th International Symposium on Therapeutic Ultrasound, ISTU 2010
CountryJapan
CityTokyo
Period6/9/106/12/10

Fingerprint

viability
waveforms
standing waves
traveling waves

Keywords

  • Cell viability
  • Standing waves
  • Ultrasound therapy
  • Wave-form dependence

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Saliev, T., Feril, L. B., McLean, D. A., Tachibana, K., & Campbell, P. A. (2011). Influence of waveform on cell viability during ultrasound exposure. In AIP Conference Proceedings (Vol. 1359, pp. 367-370) https://doi.org/10.1063/1.3607935

Influence of waveform on cell viability during ultrasound exposure. / Saliev, Timur; Feril, Loreto B.; McLean, Donald A.; Tachibana, Katsuro; Campbell, Paul A.

AIP Conference Proceedings. Vol. 1359 2011. p. 367-370.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Saliev, T, Feril, LB, McLean, DA, Tachibana, K & Campbell, PA 2011, Influence of waveform on cell viability during ultrasound exposure. in AIP Conference Proceedings. vol. 1359, pp. 367-370, 10th International Symposium on Therapeutic Ultrasound, ISTU 2010, Tokyo, Japan, 6/9/10. https://doi.org/10.1063/1.3607935
Saliev T, Feril LB, McLean DA, Tachibana K, Campbell PA. Influence of waveform on cell viability during ultrasound exposure. In AIP Conference Proceedings. Vol. 1359. 2011. p. 367-370 https://doi.org/10.1063/1.3607935
Saliev, Timur ; Feril, Loreto B. ; McLean, Donald A. ; Tachibana, Katsuro ; Campbell, Paul A. / Influence of waveform on cell viability during ultrasound exposure. AIP Conference Proceedings. Vol. 1359 2011. pp. 367-370
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