Interaction of Magnesium Ions with Semiquinone Radicals of Tiron, an Indicator of Reactive Oxygen Species

L. Yu Ustynyuk, V. A. Medvedeva, S. O. Liubimovskii, E. K. Ruuge, A. N. Tikhonov

Research output: Contribution to journalArticlepeer-review

Abstract

It has been shown using experimental (electron paramagnetic resonance) and quantum chemical (density functional theory) research methods that the previously observed changes in the electron paramagnetic resonance spectrum of the semiquinone Tiron radical in seawater are due to its interaction with Mg2+ ions. The formation of a complex between Mg2+ and the Tiron radical is due to the electrostatic attraction of ions carrying large charges of the opposite sign (+2 and –3), on the one hand, and the ability of Mg2+ ions to bind effectively to bidentate oxygen-containing ligands, on the other hand. The formation of tight contact ion pairs leads to a redistribution of the electron and spin density in the Tiron radical, which can be judged by the observed changes in the electron paramagnetic resonance spectrum of this radical.

Original languageEnglish
Pages (from-to)915-923
Number of pages9
JournalBiophysics (Russian Federation)
Volume68
Issue number6
DOIs
Publication statusPublished - Dec 2023
Externally publishedYes

Keywords

  • density functional theory
  • EPR
  • free radicals
  • magnesium chloride
  • reactive oxygen species
  • semiquinone
  • Tiron
  • water

ASJC Scopus subject areas

  • Biophysics

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