Intermolecular interactions and solvation effects of dimethylsulfoxide on type III deep eutectic solvents

Dhawal Shah, Ulan Mansurov, Farouq S. Mjalli

Research output: Contribution to journalArticle

Abstract

Reline, a typical type III Deep Eutectic Solvent (DES), composed of urea and choline chloride, is widely used and highly investigated for its thermo-physical properties and intermolecular interactions. The formation of hydrogen bonds between urea and chloride ions and a strong suppression in the hydrogen bonds between the urea molecules lead to a significantly low melting point of reline. Considering commercial applications, aqueous solutions of reline have been extensively analyzed; however, water, being a protic solvent, strongly affects the hydrogen bond network in reline and disrupts its structure. A mixture of reline with aprotic solvent has not been systematically investigated in the literature. To this end, we herein explore the intermolecular interactions between reline and dimethylsulfoxide (DMSO), a commonly used industrial solvent, which unlike water, does not have labile hydrogen. Our experiments revealed that a decrease in the density of the mixture with increasing DMSO amount is less significant as compared with water. Furthermore, molecular dynamics simulation results, as analyzed in terms of the hydrogen bonds between the components and interaction energies, suggest a very limited effect on urea-urea, urea-chloride, and urea-choline interactions in the presence of DMSO. Moreover, DMSO preferentially interacts with urea in the mixture; whereas in the case with water, the chloride ion was preferentially hydrated. Radial distribution analysis indicates that reline, while getting diluted by DMSO, maintains its structure up to 0.7-mole fraction of DMSO. Taken together the results reveal that DMSO reserves intermolecular interactions of reline better than water.

Original languageEnglish
Pages (from-to)17200-17208
Number of pages9
JournalPhysical Chemistry Chemical Physics
Volume21
Issue number31
DOIs
Publication statusPublished - Jan 1 2019

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Solvation
Dimethyl Sulfoxide
ureas
eutectics
Eutectics
solvation
Urea
Hydrogen bonds
chlorides
Water
interactions
hydrogen bonds
Chlorides
choline
water
Choline
Ions
thermophysical properties
radial distribution
melting points

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Cite this

Intermolecular interactions and solvation effects of dimethylsulfoxide on type III deep eutectic solvents. / Shah, Dhawal; Mansurov, Ulan; Mjalli, Farouq S.

In: Physical Chemistry Chemical Physics, Vol. 21, No. 31, 01.01.2019, p. 17200-17208.

Research output: Contribution to journalArticle

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