Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics -Patient Specific Model

Elnara Satekenova; Match W.L. Ko; Jong Kim

doi:10.1109/EMBC.2019.8856743

Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics -Patient Specific Model

Elnara Satekenova, Match W.L. Ko, Jong Kim

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Glaucoma is associated with damage and death of optic nerve fibers within the Lamina Cribrosa (LC) region of the Optic Nerve Head. The pathogenesis of the disease is unclear, and the anterior LC surface morphology of different individuals can be one of the possible contributor of glaucoma development and progression. The current study evaluates the relationship between the LC surface curvature and distribution of shear stresses on the LC surface. The patient-specific reconstructed ocular model was developed and analyzed in a finite element analysis software. In addition, the effect of elastic modulus of both sclera and LC on the shear stress was examined. Results showed that there is a correlation between the shear stress distribution and the curvature of the anterior LC surface. This finding highlights the potential significance of the LC morphology on the distribution of LC shear stress and require further investigation.

Original language	English
Title of host publication	2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	5370-5373
Number of pages	4
ISBN (Electronic)	9781538613115
DOIs	https://doi.org/10.1109/EMBC.2019.8856743
Publication status	Published - Jul 2019
Event	41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 - Berlin, Germany Duration: Jul 23 2019 → Jul 27 2019

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Conference

Conference	41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
Country	Germany
City	Berlin
Period	7/23/19 → 7/27/19

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

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Satekenova, E., Ko, M. W. L., & Kim, J. (2019). Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics -Patient Specific Model. In 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 (pp. 5370-5373). [8856743] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2019.8856743

Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics -Patient Specific Model. / Satekenova, Elnara; Ko, Match W.L.; Kim, Jong.

2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. p. 5370-5373 8856743 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Satekenova, E, Ko, MWL & Kim, J 2019, Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics -Patient Specific Model. in 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019., 8856743, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., pp. 5370-5373, 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019, Berlin, Germany, 7/23/19. https://doi.org/10.1109/EMBC.2019.8856743

Satekenova E, Ko MWL, Kim J. Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics -Patient Specific Model. In 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Institute of Electrical and Electronics Engineers Inc. 2019. p. 5370-5373. 8856743. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2019.8856743

Satekenova, Elnara ; Ko, Match W.L. ; Kim, Jong. / Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics -Patient Specific Model. 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 5370-5373 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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abstract = "Glaucoma is associated with damage and death of optic nerve fibers within the Lamina Cribrosa (LC) region of the Optic Nerve Head. The pathogenesis of the disease is unclear, and the anterior LC surface morphology of different individuals can be one of the possible contributor of glaucoma development and progression. The current study evaluates the relationship between the LC surface curvature and distribution of shear stresses on the LC surface. The patient-specific reconstructed ocular model was developed and analyzed in a finite element analysis software. In addition, the effect of elastic modulus of both sclera and LC on the shear stress was examined. Results showed that there is a correlation between the shear stress distribution and the curvature of the anterior LC surface. This finding highlights the potential significance of the LC morphology on the distribution of LC shear stress and require further investigation.",

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