Abstract
The possible influence of both beta-endorphin and insulin secretion on diabetes development in pregnant women was studied by means of radioimmunoassay technique (RIA-Nichols Institute). The study was carried out by determination of beta endorphins in peripheral blood samples of 28 pregnant women with gestational diabetes. They consisted of two subgroups: 14 women with insulin independence, and 14 with insulin-dependent disease. Beta endorphin increase was found in both groups, according to the progression of gestation, and the rise was significantly higher in the insulin-dependent group. At the same time, insulin application caused a marked growth of beta-endorphins in insulin-dependent group. Beta-endorphins, inhibiting insulin secretion, can influence gestional diabetes development.
| Original language | English |
|---|---|
| Pages (from-to) | 91-93 |
| Number of pages | 3 |
| Journal | Clinical and Experimental Obstetrics and Gynecology |
| Volume | 21 |
| Issue number | 2 |
| Publication status | Published - Jan 1 1994 |
| Externally published | Yes |
Keywords
- beta-endorphins
- gestational diabetes
ASJC Scopus subject areas
- Obstetrics and Gynaecology