Is there a link between beta-enrodphin and diabetes in pregnancy?

M. Terzic, B. Stimec, V. Sulovic, D. Plecas, L. J. Vojdovic

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


The possible influence of both beta-endorphin and insulin secretion on diabetes development in pregnant women was studied by means of radioimmunoassay technique (RIA-Nichols Institute). The study was carried out by determination of beta endorphins in peripheral blood samples of 28 pregnant women with gestational diabetes. They consisted of two subgroups: 14 women with insulin independence, and 14 with insulin-dependent disease. Beta endorphin increase was found in both groups, according to the progression of gestation, and the rise was significantly higher in the insulin-dependent group. At the same time, insulin application caused a marked growth of beta-endorphins in insulin-dependent group. Beta-endorphins, inhibiting insulin secretion, can influence gestional diabetes development.

Original languageEnglish
Pages (from-to)91-93
Number of pages3
JournalClinical and Experimental Obstetrics and Gynecology
Issue number2
Publication statusPublished - Jan 1 1994
Externally publishedYes


  • beta-endorphins
  • gestational diabetes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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