Abstract
A study of villus samples from eight random sites on five electively aborted chorion sacs was performed to determine any significant differences in yield, quality and composition of DNA, iduronate sulphate sulphatase activity and karyoptype status. The villi were also examined for their histological characteristics (e.g. stem, intermediate or terminal villi) and for HCG and BGP immuno‐reactivities. The overall findings indicated no significant site to site variations in any of the parameters studied. It is therefore proposed that any villus should be equally suitable for prenatal diagnosis.
Original language | English |
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Pages (from-to) | 119-127 |
Number of pages | 9 |
Journal | Prenatal Diagnosis |
Volume | 7 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 1987 |
Externally published | Yes |
Keywords
- Chorionic villus sampling
- DNA
- Prenatal diagnosis
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Genetics(clinical)