Large-scale engineered synthesis of BaTiO 3 nanoparticles using low-temperature bioinspired principles

Teyeb Ould-Ely, Matthew Luger, Lyle Kaplan-Reinig, Krisztian Niesz, Michael Doherty, Daniel E. Morse

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)


We report here a robust, large-scale synthesis of BaTiO 3 nanopowders using a bioinspired process that first was developed on a much smaller scale. The most advantageous points of this protocol are that it takes place at nearly room temperature (25 °C), overcomes many limitations encountered in other scale-up processes (such as the need for external drivers, e.g., heat, radiation or pressure), bypasses the use of surfactants and templates and does not necessitate pH adjustment. The use of a single-source, bimetallic alkoxide with the vapor diffusion of a hydrolytic catalyst (H2O) provides the necessary conditions for facile crystallization and growth of small, well-defined BaTiO3 nanoparticles at mild temperatures, yielding batches of up to 250 ± 5 g in a green process. Extension of this method to kilogram-scale production of BaTiO3 nanocrystals in semicontinuous and continuous processes is feasible.

Original languageEnglish
Pages (from-to)97-104
Number of pages8
JournalNature Protocols
Issue number1
Publication statusPublished - Jan 2011

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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