Leiomyosarcoma complicating chronic inflammation of the testis

Y. Ali, E. O. Kehinde, R. Makar, K. A. Al-Awadi, J. T. Anim

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


Objective: To report on a case of leiomyosarcoma of the testis that appeared to have arisen from a background of chronic testicular inflammation. Clinical Presentation: A 65-year-old man with a 15-year history of diabetes mellitus and low-grade discomfort and swelling in the right testis presented as an emergency with exacerbation of the pain and swelling of the testis. Repeated ultrasound examination of the testis in the past 5 years had suggested a chronic testicular inflammatory disorder. Ultrasound during the current emergency case admission revealed a normal left testis, but a large heterogeneous solid mass with a moderate intratesticular calcification in the right testis and the presence of a moderate hydrocele. Serum α-fetoprotein and β-human chorionic gonadotropin were normal. A right radical orchidectomy was performed. Histopathology and immunohistochemistry revealed primary leiomyosarcoma of the right testis. There was no spermatic cord or venous involvement. One year after orchidectomy there was no sign of metastasis. Conclusion: Radical orchidectomy followed by surveillance appears to be the treatment of choice for this testicular leiomyosarcoma, which seemed to have run an indolent course compared to other testicular tumours.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalMedical Principles and Practice
Issue number3
Publication statusPublished - 2002


  • Chronic inflammation
  • Leiomyosarcoma
  • Risk factor
  • Testis

ASJC Scopus subject areas

  • Medicine(all)

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