Lung bioaccessibility of As, Cu, Fe, Mn, Ni, Pb, and Zn in fine fraction (< 20 μm) from contaminated soils and mine tailings

Mert Guney, Clothilde M.J. Bourges, Robert P. Chapuis, Gerald J. Zagury

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The present study aims (1) to characterize contaminated soils (n = 6) and mine tailings samples (n = 3) for As, Cu, Fe, Mn, Ni, Pb, and Zn content; and (2) to assess elemental lung bioaccessibility in fine fraction (d < 20 μm which might contribute to airborne particulate matter (PM) and thus be inhaled) by means of in vitro tests using Gamble's solution (GS) and an artificial lysosomal fluid (ALF). Elemental concentrations were high in the majority of samples, particularly for As (up to 2040 mg·kg− 1), Fe (up to 30.7%), Mn (up to 4360 mg·kg− 1), and Zn (up to 4060 mg·kg− 1); and elemental concentrations (As, Cu, and Ni) in the sieved fraction (d < 20 μm) obtained from contaminated soils were significantly higher than in the bulk fraction (< 160 μm). In vitro tests with ALF yielded much higher bioaccessibility than tests with GS, and the use of ALF in addition to GS is recommended to assess lung bioaccessibility. Bioaccessibility in ALF was high for all elements after 2 weeks of testing both in terms of concentration (e.g. up to 1730 mg·kg− 1 for As) and percentages (e.g. up to 81% for Pb). The elemental solubilization rate generally declined rapidly and continuously with time. Similarly, bioaccessibility increased rapidly and tended to reach a plateau with time for most samples and metals. However, it is not possible to recommend a general testing duration as the solubilization behavior was highly element and sample-specific.

Original languageEnglish
Pages (from-to)378-386
Number of pages9
JournalScience of the Total Environment
Volume579
DOIs
Publication statusPublished - Feb 1 2017

Fingerprint

Tailings
tailings
Soils
Fluids
fluid
solubilization
Particulate Matter
Testing
particulate matter
Metals
plateau
contaminated soil
metal
test

Keywords

  • Artificial lysosomal fluid (ALF)
  • Contaminated soils
  • Gamble's solution
  • Lung bioaccessibility
  • Particulate matter (PM)
  • Toxic elements

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution

Cite this

Lung bioaccessibility of As, Cu, Fe, Mn, Ni, Pb, and Zn in fine fraction (< 20 μm) from contaminated soils and mine tailings. / Guney, Mert; Bourges, Clothilde M.J.; Chapuis, Robert P.; Zagury, Gerald J.

In: Science of the Total Environment, Vol. 579, 01.02.2017, p. 378-386.

Research output: Contribution to journalArticle

@article{362e25c603be4ee38b3b4e5ff29767e2,
title = "Lung bioaccessibility of As, Cu, Fe, Mn, Ni, Pb, and Zn in fine fraction (< 20 μm) from contaminated soils and mine tailings",
abstract = "The present study aims (1) to characterize contaminated soils (n = 6) and mine tailings samples (n = 3) for As, Cu, Fe, Mn, Ni, Pb, and Zn content; and (2) to assess elemental lung bioaccessibility in fine fraction (d < 20 μm which might contribute to airborne particulate matter (PM) and thus be inhaled) by means of in vitro tests using Gamble's solution (GS) and an artificial lysosomal fluid (ALF). Elemental concentrations were high in the majority of samples, particularly for As (up to 2040 mg·kg− 1), Fe (up to 30.7{\%}), Mn (up to 4360 mg·kg− 1), and Zn (up to 4060 mg·kg− 1); and elemental concentrations (As, Cu, and Ni) in the sieved fraction (d < 20 μm) obtained from contaminated soils were significantly higher than in the bulk fraction (< 160 μm). In vitro tests with ALF yielded much higher bioaccessibility than tests with GS, and the use of ALF in addition to GS is recommended to assess lung bioaccessibility. Bioaccessibility in ALF was high for all elements after 2 weeks of testing both in terms of concentration (e.g. up to 1730 mg·kg− 1 for As) and percentages (e.g. up to 81{\%} for Pb). The elemental solubilization rate generally declined rapidly and continuously with time. Similarly, bioaccessibility increased rapidly and tended to reach a plateau with time for most samples and metals. However, it is not possible to recommend a general testing duration as the solubilization behavior was highly element and sample-specific.",
keywords = "Artificial lysosomal fluid (ALF), Contaminated soils, Gamble's solution, Lung bioaccessibility, Particulate matter (PM), Toxic elements",
author = "Mert Guney and Bourges, {Clothilde M.J.} and Chapuis, {Robert P.} and Zagury, {Gerald J.}",
year = "2017",
month = "2",
day = "1",
doi = "10.1016/j.scitotenv.2016.11.086",
language = "English",
volume = "579",
pages = "378--386",
journal = "Science of the Total Environment",
issn = "0048-9697",
publisher = "Elsevier",

}

TY - JOUR

T1 - Lung bioaccessibility of As, Cu, Fe, Mn, Ni, Pb, and Zn in fine fraction (< 20 μm) from contaminated soils and mine tailings

AU - Guney, Mert

AU - Bourges, Clothilde M.J.

AU - Chapuis, Robert P.

AU - Zagury, Gerald J.

PY - 2017/2/1

Y1 - 2017/2/1

N2 - The present study aims (1) to characterize contaminated soils (n = 6) and mine tailings samples (n = 3) for As, Cu, Fe, Mn, Ni, Pb, and Zn content; and (2) to assess elemental lung bioaccessibility in fine fraction (d < 20 μm which might contribute to airborne particulate matter (PM) and thus be inhaled) by means of in vitro tests using Gamble's solution (GS) and an artificial lysosomal fluid (ALF). Elemental concentrations were high in the majority of samples, particularly for As (up to 2040 mg·kg− 1), Fe (up to 30.7%), Mn (up to 4360 mg·kg− 1), and Zn (up to 4060 mg·kg− 1); and elemental concentrations (As, Cu, and Ni) in the sieved fraction (d < 20 μm) obtained from contaminated soils were significantly higher than in the bulk fraction (< 160 μm). In vitro tests with ALF yielded much higher bioaccessibility than tests with GS, and the use of ALF in addition to GS is recommended to assess lung bioaccessibility. Bioaccessibility in ALF was high for all elements after 2 weeks of testing both in terms of concentration (e.g. up to 1730 mg·kg− 1 for As) and percentages (e.g. up to 81% for Pb). The elemental solubilization rate generally declined rapidly and continuously with time. Similarly, bioaccessibility increased rapidly and tended to reach a plateau with time for most samples and metals. However, it is not possible to recommend a general testing duration as the solubilization behavior was highly element and sample-specific.

AB - The present study aims (1) to characterize contaminated soils (n = 6) and mine tailings samples (n = 3) for As, Cu, Fe, Mn, Ni, Pb, and Zn content; and (2) to assess elemental lung bioaccessibility in fine fraction (d < 20 μm which might contribute to airborne particulate matter (PM) and thus be inhaled) by means of in vitro tests using Gamble's solution (GS) and an artificial lysosomal fluid (ALF). Elemental concentrations were high in the majority of samples, particularly for As (up to 2040 mg·kg− 1), Fe (up to 30.7%), Mn (up to 4360 mg·kg− 1), and Zn (up to 4060 mg·kg− 1); and elemental concentrations (As, Cu, and Ni) in the sieved fraction (d < 20 μm) obtained from contaminated soils were significantly higher than in the bulk fraction (< 160 μm). In vitro tests with ALF yielded much higher bioaccessibility than tests with GS, and the use of ALF in addition to GS is recommended to assess lung bioaccessibility. Bioaccessibility in ALF was high for all elements after 2 weeks of testing both in terms of concentration (e.g. up to 1730 mg·kg− 1 for As) and percentages (e.g. up to 81% for Pb). The elemental solubilization rate generally declined rapidly and continuously with time. Similarly, bioaccessibility increased rapidly and tended to reach a plateau with time for most samples and metals. However, it is not possible to recommend a general testing duration as the solubilization behavior was highly element and sample-specific.

KW - Artificial lysosomal fluid (ALF)

KW - Contaminated soils

KW - Gamble's solution

KW - Lung bioaccessibility

KW - Particulate matter (PM)

KW - Toxic elements

UR - http://www.scopus.com/inward/record.url?scp=85007017399&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85007017399&partnerID=8YFLogxK

U2 - 10.1016/j.scitotenv.2016.11.086

DO - 10.1016/j.scitotenv.2016.11.086

M3 - Article

VL - 579

SP - 378

EP - 386

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

ER -