Abstract
The present study aims (1) to characterize contaminated soils (n = 6) and mine tailings samples (n = 3) for As, Cu, Fe, Mn, Ni, Pb, and Zn content; and (2) to assess elemental lung bioaccessibility in fine fraction (d < 20 μm which might contribute to airborne particulate matter (PM) and thus be inhaled) by means of in vitro tests using Gamble's solution (GS) and an artificial lysosomal fluid (ALF). Elemental concentrations were high in the majority of samples, particularly for As (up to 2040 mg·kg− 1), Fe (up to 30.7%), Mn (up to 4360 mg·kg− 1), and Zn (up to 4060 mg·kg− 1); and elemental concentrations (As, Cu, and Ni) in the sieved fraction (d < 20 μm) obtained from contaminated soils were significantly higher than in the bulk fraction (< 160 μm). In vitro tests with ALF yielded much higher bioaccessibility than tests with GS, and the use of ALF in addition to GS is recommended to assess lung bioaccessibility. Bioaccessibility in ALF was high for all elements after 2 weeks of testing both in terms of concentration (e.g. up to 1730 mg·kg− 1 for As) and percentages (e.g. up to 81% for Pb). The elemental solubilization rate generally declined rapidly and continuously with time. Similarly, bioaccessibility increased rapidly and tended to reach a plateau with time for most samples and metals. However, it is not possible to recommend a general testing duration as the solubilization behavior was highly element and sample-specific.
| Original language | English |
|---|---|
| Pages (from-to) | 378-386 |
| Number of pages | 9 |
| Journal | Science of the Total Environment |
| Volume | 579 |
| DOIs | |
| Publication status | Published - Feb 1 2017 |
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Keywords
- Artificial lysosomal fluid (ALF)
- Contaminated soils
- Gamble's solution
- Lung bioaccessibility
- Particulate matter (PM)
- Toxic elements
ASJC Scopus subject areas
- Environmental Engineering
- Environmental Chemistry
- Waste Management and Disposal
- Pollution
Cite this
Lung bioaccessibility of As, Cu, Fe, Mn, Ni, Pb, and Zn in fine fraction (< 20 μm) from contaminated soils and mine tailings. / Guney, Mert; Bourges, Clothilde M.J.; Chapuis, Robert P.; Zagury, Gerald J.
In: Science of the Total Environment, Vol. 579, 01.02.2017, p. 378-386.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lung bioaccessibility of As, Cu, Fe, Mn, Ni, Pb, and Zn in fine fraction (< 20 μm) from contaminated soils and mine tailings
AU - Guney, Mert
AU - Bourges, Clothilde M.J.
AU - Chapuis, Robert P.
AU - Zagury, Gerald J.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - The present study aims (1) to characterize contaminated soils (n = 6) and mine tailings samples (n = 3) for As, Cu, Fe, Mn, Ni, Pb, and Zn content; and (2) to assess elemental lung bioaccessibility in fine fraction (d < 20 μm which might contribute to airborne particulate matter (PM) and thus be inhaled) by means of in vitro tests using Gamble's solution (GS) and an artificial lysosomal fluid (ALF). Elemental concentrations were high in the majority of samples, particularly for As (up to 2040 mg·kg− 1), Fe (up to 30.7%), Mn (up to 4360 mg·kg− 1), and Zn (up to 4060 mg·kg− 1); and elemental concentrations (As, Cu, and Ni) in the sieved fraction (d < 20 μm) obtained from contaminated soils were significantly higher than in the bulk fraction (< 160 μm). In vitro tests with ALF yielded much higher bioaccessibility than tests with GS, and the use of ALF in addition to GS is recommended to assess lung bioaccessibility. Bioaccessibility in ALF was high for all elements after 2 weeks of testing both in terms of concentration (e.g. up to 1730 mg·kg− 1 for As) and percentages (e.g. up to 81% for Pb). The elemental solubilization rate generally declined rapidly and continuously with time. Similarly, bioaccessibility increased rapidly and tended to reach a plateau with time for most samples and metals. However, it is not possible to recommend a general testing duration as the solubilization behavior was highly element and sample-specific.
AB - The present study aims (1) to characterize contaminated soils (n = 6) and mine tailings samples (n = 3) for As, Cu, Fe, Mn, Ni, Pb, and Zn content; and (2) to assess elemental lung bioaccessibility in fine fraction (d < 20 μm which might contribute to airborne particulate matter (PM) and thus be inhaled) by means of in vitro tests using Gamble's solution (GS) and an artificial lysosomal fluid (ALF). Elemental concentrations were high in the majority of samples, particularly for As (up to 2040 mg·kg− 1), Fe (up to 30.7%), Mn (up to 4360 mg·kg− 1), and Zn (up to 4060 mg·kg− 1); and elemental concentrations (As, Cu, and Ni) in the sieved fraction (d < 20 μm) obtained from contaminated soils were significantly higher than in the bulk fraction (< 160 μm). In vitro tests with ALF yielded much higher bioaccessibility than tests with GS, and the use of ALF in addition to GS is recommended to assess lung bioaccessibility. Bioaccessibility in ALF was high for all elements after 2 weeks of testing both in terms of concentration (e.g. up to 1730 mg·kg− 1 for As) and percentages (e.g. up to 81% for Pb). The elemental solubilization rate generally declined rapidly and continuously with time. Similarly, bioaccessibility increased rapidly and tended to reach a plateau with time for most samples and metals. However, it is not possible to recommend a general testing duration as the solubilization behavior was highly element and sample-specific.
KW - Artificial lysosomal fluid (ALF)
KW - Contaminated soils
KW - Gamble's solution
KW - Lung bioaccessibility
KW - Particulate matter (PM)
KW - Toxic elements
UR - http://www.scopus.com/inward/record.url?scp=85007017399&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85007017399&partnerID=8YFLogxK
U2 - 10.1016/j.scitotenv.2016.11.086
DO - 10.1016/j.scitotenv.2016.11.086
M3 - Article
VL - 579
SP - 378
EP - 386
JO - Science of the Total Environment
JF - Science of the Total Environment
SN - 0048-9697
ER -