TY - JOUR
T1 - Magnetron Sputtering of Antibacterial and Antifungal Tantalum-Copper and Niobium-Copper Coatings on Three Dimensional-Printed Porous Titanium Alloy Scaffolds
T2 - Part II
AU - Azamatov, Bagdat
AU - Borisov, Alexandr
AU - Maratuly, Bauyrzhan
AU - Dogadkin, Dmitry
AU - Safarova, Yuliya
AU - Yamanoglu, Ridvan
AU - Alontseva, Darya
N1 - Publisher Copyright:
© 2025 Johnson Matthey Public Limited Company. All rights reserved.
PY - 2025
Y1 - 2025
N2 - This is Part II of a study on the antimicrobial efficacy of tantalum-copper and niobium-copper coatings, applied via magnetron sputtering (MS) on three dimensional (3D) printed porous Ti6Al4V alloy scaffolds and gas-abrasive treated Ti6Al4V alloy, against Staphylococcus aureus and Candida albicans. Thicker coatings were found to show superior antimicrobial activity; however, thin niobium-copper coatings and uncoated alloy did not exhibit inhibitory effects. The release dynamics of copper ions from tantalum-copper coatings into physiological solution, analysed over ten days via inductively coupled plasma mass spectrometry, matched the inhibition zone growth. These findings support the potential of these coatings in developing endoprosthesis implants with enhanced antimicrobial properties.
AB - This is Part II of a study on the antimicrobial efficacy of tantalum-copper and niobium-copper coatings, applied via magnetron sputtering (MS) on three dimensional (3D) printed porous Ti6Al4V alloy scaffolds and gas-abrasive treated Ti6Al4V alloy, against Staphylococcus aureus and Candida albicans. Thicker coatings were found to show superior antimicrobial activity; however, thin niobium-copper coatings and uncoated alloy did not exhibit inhibitory effects. The release dynamics of copper ions from tantalum-copper coatings into physiological solution, analysed over ten days via inductively coupled plasma mass spectrometry, matched the inhibition zone growth. These findings support the potential of these coatings in developing endoprosthesis implants with enhanced antimicrobial properties.
KW - additive manufacturing
KW - bacterial resistance
KW - magnetron-sputtered coating
KW - selective laser melting
KW - titanium endoprosthesis implants
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U2 - 10.1595/205651325X17302963281360
DO - 10.1595/205651325X17302963281360
M3 - Article
AN - SCOPUS:85214387768
SN - 2056-5135
VL - 69
SP - 88
EP - 98
JO - Johnson Matthey Technology Review
JF - Johnson Matthey Technology Review
IS - 1
ER -