Mesoporous silica with fibrous morphology: A multifunctional core-shell platform for biomedical applications

Timur Sh Atabaev, Jong Ho Lee, Jun Jae Lee, Dong Wook Han, Yoon Hwae Hwang, Hyung Kook Kim, Nguyen Hoa Hong

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Multifunctional mesoporous silica nanocomposites are attractive carriers for targeted drug delivery in nanomedicine. Although promising developments have been made in the fabrication of multifunctional mesoporous silica nanocomposites, the design and mass production of novel multifunctional carriers are still challenging. This paper reports the facile one-pot fabrication of a multifunctional inorganic composite composed of superparamagnetic Fe 3O4 nanoparticles and coated dye-functionalized mesoporous silica with a high specific surface area. The resulting composite particles had a tunable particle size, special open pore channels with high specific surface area, which is quite favorable for drug loading and release properties, as well as luminescent and superparamagnetic properties suitable for targeted drug delivery and tracking. This composite exhibited low toxicity, suggesting potential biomedical applications.

Original languageEnglish
Article number345603
JournalNanotechnology
Volume24
Issue number34
DOIs
Publication statusPublished - Aug 30 2013
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Mechanics of Materials
  • Materials Science(all)

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