Microfluidic synthesis of advanced microparticles for encapsulation and controlled release

Wynter J. Duncanson, Tina Lin, Adam R. Abate, Sebastian Seiffert, Rhutesh K. Shah, David A. Weitz

Research output: Contribution to journalReview articlepeer-review

242 Citations (Scopus)


We describe droplet microfluidic strategies used to fabricate advanced microparticles that are useful structures for the encapsulation and release of actives; these strategies can be further developed to produce microparticles for advanced drug delivery applications. Microfluidics enables exquisite control in the fabrication of polymer vesicles and thermosensitive microgels from single and higher-order multiple emulsion templates. The strategies used to create the diversity of microparticle structures described in this review, coupled with the scalability of microfluidics, will enable fabrication of large quantities of novel microparticle structures that have potential uses in controlled drug release applications.

Original languageEnglish
Pages (from-to)2135-2145
Number of pages11
JournalLab on a Chip
Issue number12
Publication statusPublished - Jun 21 2012

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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