Molecular energy transducers of the living cell. Proton ATP synthase: A rotating molecular motor

Yu M. Romanovsky, A. N. Tikhonov

Research output: Contribution to journalReview articlepeer-review

28 Citations (Scopus)

Abstract

The free energy released upon the enzymatic hydrolysis of adenosine triphosphate (ATP) is the main source of energy for the functioning of the living cell and all multicellular organisms. The overwhelming majority of ATP molecules are formed by proton ATP synthases, which are the smallest macro-molecular electric motors in Nature. This paper reviews the modern concepts of the molecular structure and functioning of the proton ATP synthase, and real-time biophysical experiments on the rotation of the 'rotor' of this macromolecular motor. Some mathematical models describing the operation of this nanosized macromolecular machine are described.

Original languageEnglish
Pages (from-to)893-914
Number of pages22
JournalPhysics-Uspekhi
Volume53
Issue number9
DOIs
Publication statusPublished - 2010
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Fingerprint Dive into the research topics of 'Molecular energy transducers of the living cell. Proton ATP synthase: A rotating molecular motor'. Together they form a unique fingerprint.

Cite this