Higher acrylates are used in special applications. However, production at high capacity in continuous reactive distillation (RD) systems, throughout the whole year of only one acrylate, may be hindered by a low market and periodic demands. Thus, for the asset to be fully utilized, one may consider to build a multi-product reactive distillation system. This is a preliminary study that shows what four higher acrylates (i.e., isoamyl acrylate, cyclohexyl acrylate, 2-ethylhexyl acrylate and n-decyl acrylate) have in common to be considered candidates for producing them in the same column, and the methodology to design such a multi-product RD column. The systemic design method uses PSE tools to achieve the design, based solely on thermodynamics and equilibrium information.