Multicomponent Assembly of Trisubstituted Imidazoles and Their Photochemical Cyclization into Fused Polyheterocyclic Scaffolds

Diana Gapanenok; Azat Makhmet; Anatoly A. Peshkov; Darya Smirnova; Niyaz Amire; Vsevolod A. Peshkov; Darya Spiridonova; Dmitry Dar'In; Saeed Balalaie; Mikhail Krasavin

doi:10.1021/acs.joc.2c00475

Multicomponent Assembly of Trisubstituted Imidazoles and Their Photochemical Cyclization into Fused Polyheterocyclic Scaffolds

Diana Gapanenok
, Azat Makhmet
, Anatoly A. Peshkov
, Darya Smirnova
, Niyaz Amire
, Vsevolod A. Peshkov
, Darya Spiridonova
, Dmitry Dar'In
, Saeed Balalaie
, Mikhail Krasavin

St. Petersburg State University
L.N. Gumilyov Eurasian National University
Nazarbayev University
K.N. Toosi University of Technology
Immanuel Kant Baltic Federal University

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

A straightforward route to a large and diverse library of trisubstituted imidazoles was established via a three-component reaction of 2-oxoaldehydes, 1,3-dicarbonyl compounds, and acyclic nitrogen bis-nucleophiles. The obtained products were subsequently explored in a photochemical cyclization yielding a variety of imidazole-fused polycyclic compounds.

Original language	English
Pages (from-to)	7838-7851
Number of pages	14
Journal	Journal of Organic Chemistry
Volume	87
Issue number	12
DOIs	https://doi.org/10.1021/acs.joc.2c00475
Publication status	Published - Jun 17 2022

ASJC Scopus subject areas

Organic Chemistry

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10.1021/acs.joc.2c00475

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title = "Multicomponent Assembly of Trisubstituted Imidazoles and Their Photochemical Cyclization into Fused Polyheterocyclic Scaffolds",

abstract = "A straightforward route to a large and diverse library of trisubstituted imidazoles was established via a three-component reaction of 2-oxoaldehydes, 1,3-dicarbonyl compounds, and acyclic nitrogen bis-nucleophiles. The obtained products were subsequently explored in a photochemical cyclization yielding a variety of imidazole-fused polycyclic compounds.",

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T1 - Multicomponent Assembly of Trisubstituted Imidazoles and Their Photochemical Cyclization into Fused Polyheterocyclic Scaffolds

AU - Gapanenok, Diana

AU - Makhmet, Azat

AU - Peshkov, Anatoly A.

AU - Smirnova, Darya

AU - Amire, Niyaz

AU - Peshkov, Vsevolod A.

AU - Spiridonova, Darya

AU - Dar'In, Dmitry

AU - Balalaie, Saeed

AU - Krasavin, Mikhail

PY - 2022/6/17

Y1 - 2022/6/17

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AB - A straightforward route to a large and diverse library of trisubstituted imidazoles was established via a three-component reaction of 2-oxoaldehydes, 1,3-dicarbonyl compounds, and acyclic nitrogen bis-nucleophiles. The obtained products were subsequently explored in a photochemical cyclization yielding a variety of imidazole-fused polycyclic compounds.

UR - https://www.scopus.com/pages/publications/85133522409

UR - https://www.scopus.com/pages/publications/85133522409#tab=citedBy

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DO - 10.1021/acs.joc.2c00475

M3 - Article

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EP - 7851

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 12

ER -

Multicomponent Assembly of Trisubstituted Imidazoles and Their Photochemical Cyclization into Fused Polyheterocyclic Scaffolds

Abstract

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