Nanoscale pearl powder exhibits non-peroxidase activity, fluorescence and inhibits cell spreading of prostate cancer

Madi Tilegen; Qinglei Sun; Ayan Nurkesh; Balnur Bazarbayeva; Haiyan Fan; Yingqiu Xie

doi:10.1109/NEMS.2019.8915658

Nanoscale pearl powder exhibits non-peroxidase activity, fluorescence and inhibits cell spreading of prostate cancer

Madi Tilegen
, Qinglei Sun
, Ayan Nurkesh
, Balnur Bazarbayeva
, Haiyan Fan
, Yingqiu Xie

School of Sciences and Humanities

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Pearl powder is an ingredient in complex of traditional Chinese medicine in treatment on skin. However, how pearl powder affects cells especially cancer cells is unclear. Here we investigated the pearl powder electrochemical characters and biological functions. We found the major component of carbon and calcium with metals of Mn and Fe in pearl powder. The possible magnetic and non-peroxidase nanozyme activity suggest the complex functions of pearl powder in biological response. Moreover, the pearl powder at mixed nanoscale can inhibit cancer cells spreading. Our data suggest that pearl powder at mixed nanoscale can exert more efficient function in cells. Nano Chinese medicine may play complicated roles in therapy.

Original language	English
Title of host publication	Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	269-272
Number of pages	4
ISBN (Electronic)	9781728116297
DOIs	https://doi.org/10.1109/NEMS.2019.8915658
Publication status	Published - Apr 2019
Event	14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019 - Bangkok, Thailand Duration: Apr 11 2019 → Apr 14 2019

Publication series

Name	Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019

Conference

Conference	14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019
Country/Territory	Thailand
City	Bangkok
Period	4/11/19 → 4/14/19

Funding

ACKNOWLEDGMENT We would like to thank Dr. Xie’s lab all students for assistance during experiments. The research was in part funded by the Nazarbayev University Faculty-Development Competitive Research Grants Program (grant number:110119FD4531 to YX and grant number: 110119FD4542 to HF and YX) for hiring of personnel and others.

Keywords

Nanoscale
cancer
cell spreading
nano Chinese medicine
nanobiology
nanozyme
pearl powder

ASJC Scopus subject areas

Mechanical Engineering
Electronic, Optical and Magnetic Materials
Surfaces, Coatings and Films
Instrumentation

Access to Document

10.1109/NEMS.2019.8915658

Cite this

Tilegen, M., Sun, Q., Nurkesh, A., Bazarbayeva, B., Fan, H., & Xie, Y. (2019). Nanoscale pearl powder exhibits non-peroxidase activity, fluorescence and inhibits cell spreading of prostate cancer. In Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019 (pp. 269-272). Article 8915658 (Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NEMS.2019.8915658

Nanoscale pearl powder exhibits non-peroxidase activity, fluorescence and inhibits cell spreading of prostate cancer. / Tilegen, Madi; Sun, Qinglei; Nurkesh, Ayan et al.
Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019. Institute of Electrical and Electronics Engineers Inc., 2019. p. 269-272 8915658 (Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Tilegen, M, Sun, Q, Nurkesh, A, Bazarbayeva, B, Fan, H & Xie, Y 2019, Nanoscale pearl powder exhibits non-peroxidase activity, fluorescence and inhibits cell spreading of prostate cancer. in Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019., 8915658, Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019, Institute of Electrical and Electronics Engineers Inc., pp. 269-272, 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019, Bangkok, Thailand, 4/11/19. https://doi.org/10.1109/NEMS.2019.8915658

Tilegen M, Sun Q, Nurkesh A, Bazarbayeva B, Fan H , Xie Y. Nanoscale pearl powder exhibits non-peroxidase activity, fluorescence and inhibits cell spreading of prostate cancer. In Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019. Institute of Electrical and Electronics Engineers Inc. 2019. p. 269-272. 8915658. (Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019). doi: 10.1109/NEMS.2019.8915658

Tilegen, Madi ; Sun, Qinglei ; Nurkesh, Ayan et al. / Nanoscale pearl powder exhibits non-peroxidase activity, fluorescence and inhibits cell spreading of prostate cancer. Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 269-272 (Proceedings of the 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2019).

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abstract = "Pearl powder is an ingredient in complex of traditional Chinese medicine in treatment on skin. However, how pearl powder affects cells especially cancer cells is unclear. Here we investigated the pearl powder electrochemical characters and biological functions. We found the major component of carbon and calcium with metals of Mn and Fe in pearl powder. The possible magnetic and non-peroxidase nanozyme activity suggest the complex functions of pearl powder in biological response. Moreover, the pearl powder at mixed nanoscale can inhibit cancer cells spreading. Our data suggest that pearl powder at mixed nanoscale can exert more efficient function in cells. Nano Chinese medicine may play complicated roles in therapy.",

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AU - Bazarbayeva, Balnur

AU - Fan, Haiyan

AU - Xie, Yingqiu

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AB - Pearl powder is an ingredient in complex of traditional Chinese medicine in treatment on skin. However, how pearl powder affects cells especially cancer cells is unclear. Here we investigated the pearl powder electrochemical characters and biological functions. We found the major component of carbon and calcium with metals of Mn and Fe in pearl powder. The possible magnetic and non-peroxidase nanozyme activity suggest the complex functions of pearl powder in biological response. Moreover, the pearl powder at mixed nanoscale can inhibit cancer cells spreading. Our data suggest that pearl powder at mixed nanoscale can exert more efficient function in cells. Nano Chinese medicine may play complicated roles in therapy.

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Nanoscale pearl powder exhibits non-peroxidase activity, fluorescence and inhibits cell spreading of prostate cancer

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Keywords

ASJC Scopus subject areas

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