Network copolymers of acrylic and methacrylic acids: Hydrophilic ointment bases for wound-healing preparations

E. M. Tazhbaev; R. N. Pak; S. B. Akhmetova; M. Zh Burkeev; A. E. Gulyaev; S. M. Adekenov

doi:10.1007/s11094-007-0114-2

Network copolymers of acrylic and methacrylic acids: Hydrophilic ointment bases for wound-healing preparations

E. M. Tazhbaev, R. N. Pak, S. B. Akhmetova, M. Zh Burkeev, A. E. Gulyaev, S. M. Adekenov

Research output: Contribution to journal › Article › peer-review

Abstract

Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.

Original language	English
Pages (from-to)	508-511
Number of pages	4
Journal	Pharmaceutical Chemistry Journal
Volume	41
Issue number	9
DOIs	https://doi.org/10.1007/s11094-007-0114-2
Publication status	Published - Sep 2007
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Drug Discovery

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abstract = "Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.",

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AU - Tazhbaev, E. M.

AU - Pak, R. N.

AU - Akhmetova, S. B.

AU - Burkeev, M. Zh

AU - Gulyaev, A. E.

AU - Adekenov, S. M.

PY - 2007/9

Y1 - 2007/9

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AB - Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.

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JO - Pharmaceutical Chemistry Journal

JF - Pharmaceutical Chemistry Journal

SN - 0091-150X

IS - 9

ER -

Network copolymers of acrylic and methacrylic acids: Hydrophilic ointment bases for wound-healing preparations

Abstract

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