Abstract
Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.
| Original language | English |
|---|---|
| Pages (from-to) | 508-511 |
| Number of pages | 4 |
| Journal | Pharmaceutical Chemistry Journal |
| Volume | 41 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sep 1 2007 |
| Externally published | Yes |
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery
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Tazhbaev, E. M., Pak, R. N., Akhmetova, S. B., Burkeev, M. Z., Gulyaev, A. E., & Adekenov, S. M. (2007). Network copolymers of acrylic and methacrylic acids: Hydrophilic ointment bases for wound-healing preparations. Pharmaceutical Chemistry Journal, 41(9), 508-511. https://doi.org/10.1007/s11094-007-0114-2