Abstract
Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.
| Original language | English |
|---|---|
| Pages (from-to) | 508-511 |
| Number of pages | 4 |
| Journal | Pharmaceutical Chemistry Journal |
| Volume | 41 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sep 2007 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology, Toxicology and Pharmaceutics(all)
Cite this
Network copolymers of acrylic and methacrylic acids : Hydrophilic ointment bases for wound-healing preparations. / Tazhbaev, E. M.; Pak, R. N.; Akhmetova, S. B.; Burkeev, M. Zh; Gulyaev, A. E.; Adekenov, S. M.
In: Pharmaceutical Chemistry Journal, Vol. 41, No. 9, 09.2007, p. 508-511.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Network copolymers of acrylic and methacrylic acids
T2 - Hydrophilic ointment bases for wound-healing preparations
AU - Tazhbaev, E. M.
AU - Pak, R. N.
AU - Akhmetova, S. B.
AU - Burkeev, M. Zh
AU - Gulyaev, A. E.
AU - Adekenov, S. M.
PY - 2007/9
Y1 - 2007/9
N2 - Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.
AB - Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.
UR - http://www.scopus.com/inward/record.url?scp=40049084466&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40049084466&partnerID=8YFLogxK
U2 - 10.1007/s11094-007-0114-2
DO - 10.1007/s11094-007-0114-2
M3 - Article
AN - SCOPUS:40049084466
VL - 41
SP - 508
EP - 511
JO - Pharmaceutical Chemistry Journal
JF - Pharmaceutical Chemistry Journal
SN - 0091-150X
IS - 9
ER -