Network copolymers of acrylic and methacrylic acids: Hydrophilic ointment bases for wound-healing preparations

E. M. Tazhbaev, R. N. Pak, S. B. Akhmetova, M. Zh Burkeev, A. E. Gulyaev, S. M. Adekenov

Research output: Contribution to journalArticle

Abstract

Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.

Original languageEnglish
Pages (from-to)508-511
Number of pages4
JournalPharmaceutical Chemistry Journal
Volume41
Issue number9
DOIs
Publication statusPublished - Sep 2007
Externally publishedYes

Fingerprint

Ointment Bases
Wound Healing
Artemisia
Polymers
Oils
Peptide Hydrolases
methacrylic acid
acrylic acid

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Network copolymers of acrylic and methacrylic acids : Hydrophilic ointment bases for wound-healing preparations. / Tazhbaev, E. M.; Pak, R. N.; Akhmetova, S. B.; Burkeev, M. Zh; Gulyaev, A. E.; Adekenov, S. M.

In: Pharmaceutical Chemistry Journal, Vol. 41, No. 9, 09.2007, p. 508-511.

Research output: Contribution to journalArticle

Tazhbaev, E. M. ; Pak, R. N. ; Akhmetova, S. B. ; Burkeev, M. Zh ; Gulyaev, A. E. ; Adekenov, S. M. / Network copolymers of acrylic and methacrylic acids : Hydrophilic ointment bases for wound-healing preparations. In: Pharmaceutical Chemistry Journal. 2007 ; Vol. 41, No. 9. pp. 508-511.
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