Network copolymers of acrylic and methacrylic acids: Hydrophilic ointment bases for wound-healing preparations

E. M. Tazhbaev, R. N. Pak, S. B. Akhmetova, M. Zh Burkeev, A. E. Gulyaev, S. M. Adekenov

Research output: Contribution to journalArticlepeer-review

Abstract

Investigations aimed at the development of a combined wound-healing preparation on a hydrophilic ointment base have been carried out. Copolymers of acrylic acid and its derivatives with a new divinyl monomer, β-vinyloxyethylamide of acrylic acid, are proposed as the bases. It is established that these ointment bases exhibit sufficiently high osmotic activity. Polymer-based complexes including the ethereal oil of smooth wormwood and the proteolytic enzyme protosubtilin showed pronounced antibacterial and wound-healing activity.

Original languageEnglish
Pages (from-to)508-511
Number of pages4
JournalPharmaceutical Chemistry Journal
Volume41
Issue number9
DOIs
Publication statusPublished - Sep 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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