New and conventional pore size tests in virus-removing membranes

Aviv Duek, Elizabeth Arkhangelsky, Ronit Krush, Asher Brenner, Vitaly Gitis

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Microorganisms are retained by ultrafiltration (UF) membranes mainly due to size exclusion. The sizes of viruses and membrane pores are close to each other and retention of viruses can be guaranteed only if the precise pore diameter is known. Unfortunately and rather surprisingly, there is no direct method to determine the membrane pore size. As a result, the UF membranes are not trusted to remove the viruses, and the treatment plants are required to enhance viral disinfection. Here we propose a new, simple and effective method for UF pore size determination using aquasols of gold and silver nanoparticles. We synthesized highly monodispersed suspensions ranging in diameter from 3 to 50 nm, which were later transferred through polymer and ceramic UF membranes. The retention percentage was plotted against the particle diameter to determine the pore size for which a membrane has a retention capability of 50, 90 and 100%. The d 50, d 90 and d 100 values were compared with data obtained from conventional transmembrane flux, polyethylene glycol, and dextran tests, and with the retention of phi X 174 and MS2 bacteriophages. The absolute pore size, d 100, for the majority of tested UF membranes is within 40-50 nm, and can only be detected with the new tests. The average 1.2 log retention of hydrophilic phi X 174 was predicted accurately by models based on the virus hydrodynamic radii and d 100 pore size. The 2.5 log MS2 retention suggests hydrophobic interactions in addition to simple ball-through-cylinder geometry.

Original languageEnglish
Pages (from-to)2505-2514
Number of pages10
JournalWater Research
Volume46
Issue number8
DOIs
Publication statusPublished - May 15 2012
Externally publishedYes

Fingerprint

Viruses
Pore size
virus
Ultrafiltration
ultrafiltration
membrane
Membranes
Size determination
Bacteriophages
Dextran
Disinfection
bacteriophage
test
Microorganisms
disinfection
ceramics
Polyethylene glycols
silver
Silver
Hydrodynamics

Keywords

  • Aquasols
  • Molecular separation
  • Monodispersed nanoparticles
  • Pathogens
  • Porous materials

ASJC Scopus subject areas

  • Water Science and Technology
  • Waste Management and Disposal
  • Pollution
  • Ecological Modelling

Cite this

New and conventional pore size tests in virus-removing membranes. / Duek, Aviv; Arkhangelsky, Elizabeth; Krush, Ronit; Brenner, Asher; Gitis, Vitaly.

In: Water Research, Vol. 46, No. 8, 15.05.2012, p. 2505-2514.

Research output: Contribution to journalArticle

Duek, Aviv ; Arkhangelsky, Elizabeth ; Krush, Ronit ; Brenner, Asher ; Gitis, Vitaly. / New and conventional pore size tests in virus-removing membranes. In: Water Research. 2012 ; Vol. 46, No. 8. pp. 2505-2514.
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