Non-extensive trends in the size distribution of coding and non-coding DNA sequences in the human genome

Th Oikonomou, A. Provata

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We study the primary DNA structure of four of the most completely sequenced human chromosomes (including chromosome 19 which is the most dense in coding), using non-extensive statistics. We show that the exponents governing the spatial decay of the coding size distributions vary between 5.2 ≤ r ≤ 5.7 for the short scales and 1.45 ≤ q ≤ 1.50 for the large scales. On the contrary, the exponents governing the spatial decay of the non-coding size distributions in these four chromosomes, take the values 2.4 ≤ r ≤ 3.2 for the short scales and 1.50 ≤ q ≤ 1.72 for the large scales. These results, in particular the values of the tail exponent q, indicate the existence of correlations in the coding and non-coding size distributions with tendency for higher correlations in the non-coding DNA.

Original languageEnglish
Pages (from-to)259-264
Number of pages6
JournalEuropean Physical Journal B
Volume50
Issue number1-2
DOIs
Publication statusPublished - Mar 1 2006

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ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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