Numerical analysis of transient blood flow characteristics of the circle of Willis

Na Shen, Qi Yuan, Zhen Chen, Changcong Cui, Yong Zhao

Research output: Contribution to journalArticlepeer-review


A two-dimensional model of the Circle of Willis(CoW) was employed to investigate the blood flow in communicating arteries, with healthy and blocked left internal carotid artery (LICA). The variations of blood flow, rates at communicating arteries in healthy CoWs, as well as unhealthy ones with blocked communicating arteries or the proximal segment of anterior cerebral artery (ACA-A1), were calculated and analyzed. According to the results, the flow rates in communicating arteries vary most obviously in the geometry of blocked LICA and missed right A1(R_A1); the curve of flow rate at anterior communication artery (ACoA) gets similar to the one at left distal segment of anterior cerebral artery (L_A2) or RA2 as left A1 or right A1 missing; the direction of flow in the left posterior communication artery (L_PCoA) changes as severe stenosis of (L_ICA) in the balanced geometry with blocked LICA, the flow rate in ACoA is greater than PCoA.

Original languageEnglish
Pages (from-to)539-543
Number of pages5
JournalYingyong Lixue Xuebao/Chinese Journal of Applied Mechanics
Issue number3
Publication statusPublished - Sept 1 2009


  • Artery stenosis
  • Blood dynamics
  • Circle of Willis
  • Transient flow

ASJC Scopus subject areas

  • Mechanics of Materials
  • Mechanical Engineering


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