Optical fiber biocompatible sensors for monitoring selective treatment of tumors via thermal ablation

Daniele Tosi, Sven Poeggel, Duraibabu B. Dinesh, Edoardo G. Macchi, Mario Gallati, Giovanni Braschi, Gabriel Leen, Elfed Lewis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Thermal ablation (TA) is an interventional procedure for selective treatment of tumors, that results in low-invasive outpatient care. The lack of real-time control of TA is one of its main weaknesses. Miniature and biocompatible optical fiber sensors are applied to achieve a dense, multi-parameter monitoring, that can substantially improve the control of TA. Ex vivo measurements are reported performed on porcine liver tissue, to reproduce radiofrequency ablation of hepatocellular carcinoma. Our measurement campaign has a two-fold focus: (1) dual pressure-temperature measurement with a single probe; (2) distributed thermal measurement to estimate point-by-point cells mortality.

Original languageEnglish
Title of host publication24th International Conference on Optical Fibre Sensors, OFS 2015
EditorsHypolito Jose Kalinowski, Jose Luis Fabris, Wojtek J. Bock
PublisherSPIE
ISBN (Electronic)9781628418392
DOIs
Publication statusPublished - Jan 1 2015
Externally publishedYes
Event24th International Conference on Optical Fibre Sensors, OFS 2015 - Curitiba, Brazil
Duration: Sep 28 2015Oct 2 2015

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9634
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Other

Other24th International Conference on Optical Fibre Sensors, OFS 2015
CountryBrazil
CityCuritiba
Period9/28/1510/2/15

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Keywords

  • Biophysical sensors
  • Distributed sensors
  • Extrinsic fabry-perot interferometry (EFPI)
  • Fiber bragg grating (FBG)
  • Hyperthermia
  • Interventional cancer care
  • Optical fiber sensors (OFS)
  • Radiofrequency ablation (RFA)

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Tosi, D., Poeggel, S., Dinesh, D. B., Macchi, E. G., Gallati, M., Braschi, G., Leen, G., & Lewis, E. (2015). Optical fiber biocompatible sensors for monitoring selective treatment of tumors via thermal ablation. In H. J. Kalinowski, J. L. Fabris, & W. J. Bock (Eds.), 24th International Conference on Optical Fibre Sensors, OFS 2015 [963428] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 9634). SPIE. https://doi.org/10.1117/12.2192201