TY - JOUR
T1 - Optimal fosamprenavir regimen to prevent lipid abnormalities
AU - Lattuada, Emanuela
AU - Lanzafame, Massimiliano
AU - Grosso, Carmela
AU - Soldani, Fabio
AU - Corsini, Fabiana
AU - Storato, Silvia
AU - Vento, Sandro
PY - 2009/12/1
Y1 - 2009/12/1
N2 - We report our experience on the impact of different fosamprenavir boosted regimens on plasma lipid levels in 48 naïve monoinfectd- HIV-seropositive patients. Eighteen months after starting antiretroviral therapy (ART), all patients showed a good immuno-virological response, with no statistically significant differences among the three groups; no changes in ART regimens were necessary and no adverse events were reported. On the contrary, a statistically significant difference among the three groups of patients was observed in cholesterol and triglyceride levels, since higher levels of cholesterol (including LDLs) and triglycerides were observed in patients taking the higher dose of ritonavir.
AB - We report our experience on the impact of different fosamprenavir boosted regimens on plasma lipid levels in 48 naïve monoinfectd- HIV-seropositive patients. Eighteen months after starting antiretroviral therapy (ART), all patients showed a good immuno-virological response, with no statistically significant differences among the three groups; no changes in ART regimens were necessary and no adverse events were reported. On the contrary, a statistically significant difference among the three groups of patients was observed in cholesterol and triglyceride levels, since higher levels of cholesterol (including LDLs) and triglycerides were observed in patients taking the higher dose of ritonavir.
KW - Cholesterol level
KW - Fosamprenavir
KW - Ritonavir
KW - Triglycerides levels
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M3 - Article
C2 - 20578411
AN - SCOPUS:77955899168
VL - 80
SP - 200
EP - 202
JO - Acta Biomedica de l'Ateneo Parmense
JF - Acta Biomedica de l'Ateneo Parmense
SN - 0392-4203
IS - 3
ER -