TY - JOUR
T1 - Paediatric severe chronic spontaneous urticaria
T2 - successful management through conventional drug therapy
AU - Poddighe, Dimitri
AU - Brambilla, Ilaria
AU - Licari, Amelia
AU - Marseglia, Gian Luigi
N1 - © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2019/8/15
Y1 - 2019/8/15
N2 - Chronic spontaneous urticaria (CSU) can occur in children and the clinical management is quite challenging. Here, we described a paediatric clinical case of CSU successfully managed by conventional therapy, including systemic steroids, cetirizine, anti-leukotriene drug and dietary restriction (for histamine-releasing foods). This patient showed neither atopy nor any allergic sensitisation; moreover, the autologous serum skin test resulted negative. This category of patients with no comorbidity and no evidence of atopy might benefit from the conventional drug management; however, a protracted course of steroid treatment with very slow and gradual tapering may be needed. This approach was successful and safe in our clinical case, but a careful follow-up, due to the potential side effects of steroids, should be recommended.
AB - Chronic spontaneous urticaria (CSU) can occur in children and the clinical management is quite challenging. Here, we described a paediatric clinical case of CSU successfully managed by conventional therapy, including systemic steroids, cetirizine, anti-leukotriene drug and dietary restriction (for histamine-releasing foods). This patient showed neither atopy nor any allergic sensitisation; moreover, the autologous serum skin test resulted negative. This category of patients with no comorbidity and no evidence of atopy might benefit from the conventional drug management; however, a protracted course of steroid treatment with very slow and gradual tapering may be needed. This approach was successful and safe in our clinical case, but a careful follow-up, due to the potential side effects of steroids, should be recommended.
U2 - 10.1136/bcr-2019-230925
DO - 10.1136/bcr-2019-230925
M3 - Article
C2 - 31420440
VL - 12
JO - BMJ Case Reports
JF - BMJ Case Reports
SN - 1757-790X
IS - 8
ER -