Pathologic criteria to estimate the state of the liver in potential donors

Caliya Shaimardanova, Galina Fedotovskikh, Aleksandr Savchuk, Ainura Doszhan, Aigerim Smagulova, Abduzhappar Gaipov

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: The pathologic evaluation of the liver is one of the most important issues in liver transplants. We evaluated the histopathological condition of livers in potential donors. Materials and Methods: After liver biopsy, 37 potential donor livers were histologically studied. Liver tissue was stained by hematoxylin and eosin as well as Masson Trichrome. Results: The results of the study showed the morphologic criteria used to estimate the state of the liver in potential donors is not only steatosis and fibrosis, but other important histologic criteria, such as proteinosis, necrosis of hepatocytes, endotheliitis of central veins, inflammatory infiltration, endarteritis in portal tracts and phlebitis in portal tracts, proliferation of the bile ducts, and cholestasis. Conclusions: Results of the study showed that the morphologic criteria to estimate the state of the liver in potential donors includes not only steatosis and fibrosis, but other important histologic criteria as well.

Original languageEnglish
Pages (from-to)33-35
Number of pages3
JournalExperimental and Clinical Transplantation
Volume13
DOIs
Publication statusPublished - Nov 1 2015
Externally publishedYes

Keywords

  • Donor
  • Liver tissue
  • Microscopy
  • Morphology

ASJC Scopus subject areas

  • Transplantation

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