TY - GEN
T1 - Physical and biological properties of TiNbTa alloy
AU - Pogrebnjak, Alexander
AU - Kimossov, Ruslan
AU - Myakinin, Alexandr
AU - Plotnikov, Sergey
AU - Turlybekuly, Amanzhol
AU - Zhanyssov, Syrym
AU - Kistaubayeva, Aida
AU - Shokataeva, Dina
AU - Tsorayev, Alexey
N1 - Publisher Copyright:
© 2018 IEEE.
PY - 2018/9
Y1 - 2018/9
N2 - This work is devoted to obtaining a superelastic alloy with acceptable biomechanical parameters, investigation of mechanical properties and cytotoxicity. An ingot of TiNbTa alloy (titanium-niobium-tantalum) was smelted by two remelting in an arc furnace vacuum furnace. The alloy samples were analyzed by scanning electron microscopy (SEM) using the JSM-6390LV microscope with the energy dispersive microanalysis system INCA Energy Penta FET X3. The biocompatibility of composite materials under in vitro conditions was assessed by the following indices: viability level, adhesive properties, morphology, cell proliferation and differentiation. Cell viability was determined after 72 and 120 hours using the trypan blue dye exclusion test to selectively stain dead cells. The number of non-staining cells was counted using an electronic BID-RAD TC20 cell counter. Biological certification in vitro has shown that Ti-Nb-Ta alloys have no cytotoxic effect, have high biological activity and exhibit antibacterial effect, which allows them to be recommended for use in medicine.
AB - This work is devoted to obtaining a superelastic alloy with acceptable biomechanical parameters, investigation of mechanical properties and cytotoxicity. An ingot of TiNbTa alloy (titanium-niobium-tantalum) was smelted by two remelting in an arc furnace vacuum furnace. The alloy samples were analyzed by scanning electron microscopy (SEM) using the JSM-6390LV microscope with the energy dispersive microanalysis system INCA Energy Penta FET X3. The biocompatibility of composite materials under in vitro conditions was assessed by the following indices: viability level, adhesive properties, morphology, cell proliferation and differentiation. Cell viability was determined after 72 and 120 hours using the trypan blue dye exclusion test to selectively stain dead cells. The number of non-staining cells was counted using an electronic BID-RAD TC20 cell counter. Biological certification in vitro has shown that Ti-Nb-Ta alloys have no cytotoxic effect, have high biological activity and exhibit antibacterial effect, which allows them to be recommended for use in medicine.
KW - Biocompatibility
KW - Cytotoxicity
KW - Implants
KW - Ti-Nb-Ta
KW - Titanium-based alloys
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U2 - 10.1109/NAP.2018.8915338
DO - 10.1109/NAP.2018.8915338
M3 - Conference contribution
AN - SCOPUS:85076804563
T3 - Proceedings of the 2018 IEEE 8th International Conference on Nanomaterials: Applications and Properties, NAP 2018
BT - Proceedings of the 2018 IEEE 8th International Conference on Nanomaterials
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 8th IEEE International Conference on Nanomaterials: Applications and Properties, NAP 2018
Y2 - 9 September 2018 through 14 September 2018
ER -