Abstract
Background: Asparagus racemosus is a climber shrub used in Indian medicine for centuries. It has been used as galactogogue and nerve tonic in folk medicine. The recent research on A. racemosus has revealed its disease fighting properties such as anti-bacterial, immunomodulatory, cardio protective, anti-stress, etc. Phytochemicals present in the plants are associated with their therapeutic capabilities. Hence, phytochemical screening of a therapeutic plant is essential. Materials and Methods: A preliminary qualitative screening of phytoconstituents present in the ethanol and aqueous extract of the plant was done. high-performance thin layer chromatography (HPTLC) was used to create a phytochemical fingerprint of the plant extract. Further, a series of antioxidant assays, i.e., 2,2-diphenyl-1-picrylhydrazyl (DDPH) radical, Nitric oxide (NO) radical, Superoxide (SO) radical and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging assays were done. Results: The phytochemical screening and the HPTLC fingerprint showed the presence of phenolic compounds, flavonoids, glycosides, triterpenoids, saponins etc. They also showed free radical scavenging property and hence can be used as potential primary antioxidant. Conclusion: A preliminary screening created a phytochemical profile of A. racemosus extracts. These phytoconstituents may be linked to the various known therapeutic applications of the plant. This may aid in further extensive studies for identifying and isolating compounds with potential therapeutic value in A. racemosus.
| Original language | English |
|---|---|
| Pages (from-to) | 818-823 |
| Number of pages | 6 |
| Journal | Pharmacognosy Journal |
| Volume | 11 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jan 1 2019 |
| Externally published | Yes |
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Keywords
- Antioxidants
- Asparagus racemosus
- Chromatography
- Phytochemistry
- Phytoconstituents
- Therapeutics
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery
Cite this
Phytochemical Screening, HPTLC Fingerprinting and Invitro Antioxidant Activity of Root Extract of Asparagus racemosus. / Selvaraj, Kalaivani; Sivakumar, Girija; Pillai, Aruthra Arumugam; Veeraraghavan, Vishnu Priya; Bolla, Srinivasa Rao; Veeraraghavan, Geetha Royapuram; Rengasamy, Gayathri; Joseph, Joel P.; Janardhana, P. B.
In: Pharmacognosy Journal, Vol. 11, No. 4, 01.01.2019, p. 818-823.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Phytochemical Screening, HPTLC Fingerprinting and Invitro Antioxidant Activity of Root Extract of Asparagus racemosus
AU - Selvaraj, Kalaivani
AU - Sivakumar, Girija
AU - Pillai, Aruthra Arumugam
AU - Veeraraghavan, Vishnu Priya
AU - Bolla, Srinivasa Rao
AU - Veeraraghavan, Geetha Royapuram
AU - Rengasamy, Gayathri
AU - Joseph, Joel P.
AU - Janardhana, P. B.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Background: Asparagus racemosus is a climber shrub used in Indian medicine for centuries. It has been used as galactogogue and nerve tonic in folk medicine. The recent research on A. racemosus has revealed its disease fighting properties such as anti-bacterial, immunomodulatory, cardio protective, anti-stress, etc. Phytochemicals present in the plants are associated with their therapeutic capabilities. Hence, phytochemical screening of a therapeutic plant is essential. Materials and Methods: A preliminary qualitative screening of phytoconstituents present in the ethanol and aqueous extract of the plant was done. high-performance thin layer chromatography (HPTLC) was used to create a phytochemical fingerprint of the plant extract. Further, a series of antioxidant assays, i.e., 2,2-diphenyl-1-picrylhydrazyl (DDPH) radical, Nitric oxide (NO) radical, Superoxide (SO) radical and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging assays were done. Results: The phytochemical screening and the HPTLC fingerprint showed the presence of phenolic compounds, flavonoids, glycosides, triterpenoids, saponins etc. They also showed free radical scavenging property and hence can be used as potential primary antioxidant. Conclusion: A preliminary screening created a phytochemical profile of A. racemosus extracts. These phytoconstituents may be linked to the various known therapeutic applications of the plant. This may aid in further extensive studies for identifying and isolating compounds with potential therapeutic value in A. racemosus.
AB - Background: Asparagus racemosus is a climber shrub used in Indian medicine for centuries. It has been used as galactogogue and nerve tonic in folk medicine. The recent research on A. racemosus has revealed its disease fighting properties such as anti-bacterial, immunomodulatory, cardio protective, anti-stress, etc. Phytochemicals present in the plants are associated with their therapeutic capabilities. Hence, phytochemical screening of a therapeutic plant is essential. Materials and Methods: A preliminary qualitative screening of phytoconstituents present in the ethanol and aqueous extract of the plant was done. high-performance thin layer chromatography (HPTLC) was used to create a phytochemical fingerprint of the plant extract. Further, a series of antioxidant assays, i.e., 2,2-diphenyl-1-picrylhydrazyl (DDPH) radical, Nitric oxide (NO) radical, Superoxide (SO) radical and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging assays were done. Results: The phytochemical screening and the HPTLC fingerprint showed the presence of phenolic compounds, flavonoids, glycosides, triterpenoids, saponins etc. They also showed free radical scavenging property and hence can be used as potential primary antioxidant. Conclusion: A preliminary screening created a phytochemical profile of A. racemosus extracts. These phytoconstituents may be linked to the various known therapeutic applications of the plant. This may aid in further extensive studies for identifying and isolating compounds with potential therapeutic value in A. racemosus.
KW - Antioxidants
KW - Asparagus racemosus
KW - Chromatography
KW - Phytochemistry
KW - Phytoconstituents
KW - Therapeutics
UR - http://www.scopus.com/inward/record.url?scp=85071275888&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85071275888&partnerID=8YFLogxK
U2 - 10.5530/pj.2019.11.131
DO - 10.5530/pj.2019.11.131
M3 - Article
VL - 11
SP - 818
EP - 823
JO - Pharmacognosy Journal
JF - Pharmacognosy Journal
SN - 0975-3575
IS - 4
ER -