TY - JOUR
T1 - Pipelle endometrial sampling success rates in Kazakhstani settings
T2 - results from a prospective cohort analysis
AU - Terzic, Milan
AU - Aimagambetova, Gulzhanat
AU - Bapayeva, Gauri
AU - Ukybassova, Talshyn
AU - Kenbayeva, Kamila
AU - Kaiyrlykyzy, Aiym
AU - Ibrayimov, Bakytkali
AU - Lyasova, Alla
AU - Terzic, Sanja
AU - Alkatout, Ibrahim
AU - Gitas, Georgios
AU - Hortu, İsmet
AU - Garzon, Simone
AU - Laganà, Antonio Simone
N1 - Funding Information:
This study was supported by the Nazarbayev University Grant [Number 110119FD4540, 2019-2022]. We would like to recognize Dr. Faina Linkov, University of Pittsburgh, Pittsburgh, PA, USA. FL guided the development of the protocols for this study and IRB materials. She also helped with the preparation of the manuscript.
Publisher Copyright:
© 2021 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022
Y1 - 2022
N2 - The aim of this study was to evaluate the feasibility of Pipelle endometrial sampling and to explore factors influencing Pipelle success rate in the clinical settings of Kazakhstan. This prospective analysis included 87 patients who had undergone Pipelle biopsy due to medical indications for endometrial sampling. We analysed physician and patient-related factors potentially influencing the success rate of this method. Pipelle endometrial biopsy overall success rate was 82.76%. The indications for the procedure and patients’ age were key factors influencing Pipelle sampling success (p <.001). The success rate was the highest in the group with abnormal uterine bleeding as a biopsy indication in the reproductive age group (93.19%; p <.001). Pipelle biopsy was found to be an acceptable option for endometrial sampling in our clinical setting; at the same time, physicians should consider the potential influencing factors on its success rate like indications for the procedure, BMI and patients’ age as well as their menopausal status. In order to provide precise future directions, there is a need to study a larger number of patients.IMPACT STATEMENTWhat is already known on this subject? Compared to dilation and curettage sampling conducted in the operation room, Pipelle endometrial sampling is relatively inexpensive, associated with less morbidity, safe, accurate, and can be performed in an office setting. What do the results of this study add? This is the first prospective data analysis about Pipelle endometrial sampling in Kazakhstani population. What are the implications of these findings for clinical practice and/or further research? Enabling the timely diagnosis of current endometrial pathology, Pipelle endometrial sampling approach may have an important impact on healthcare safety and efficiency, and improve overall treatment outcomes and the quality of life of Kazakhstani population if used consistently.
AB - The aim of this study was to evaluate the feasibility of Pipelle endometrial sampling and to explore factors influencing Pipelle success rate in the clinical settings of Kazakhstan. This prospective analysis included 87 patients who had undergone Pipelle biopsy due to medical indications for endometrial sampling. We analysed physician and patient-related factors potentially influencing the success rate of this method. Pipelle endometrial biopsy overall success rate was 82.76%. The indications for the procedure and patients’ age were key factors influencing Pipelle sampling success (p <.001). The success rate was the highest in the group with abnormal uterine bleeding as a biopsy indication in the reproductive age group (93.19%; p <.001). Pipelle biopsy was found to be an acceptable option for endometrial sampling in our clinical setting; at the same time, physicians should consider the potential influencing factors on its success rate like indications for the procedure, BMI and patients’ age as well as their menopausal status. In order to provide precise future directions, there is a need to study a larger number of patients.IMPACT STATEMENTWhat is already known on this subject? Compared to dilation and curettage sampling conducted in the operation room, Pipelle endometrial sampling is relatively inexpensive, associated with less morbidity, safe, accurate, and can be performed in an office setting. What do the results of this study add? This is the first prospective data analysis about Pipelle endometrial sampling in Kazakhstani population. What are the implications of these findings for clinical practice and/or further research? Enabling the timely diagnosis of current endometrial pathology, Pipelle endometrial sampling approach may have an important impact on healthcare safety and efficiency, and improve overall treatment outcomes and the quality of life of Kazakhstani population if used consistently.
KW - Abnormal uterine bleeding
KW - Pipelle biopsy
KW - dilatation and curettage
KW - endometrial hyperplasia
KW - endometrial sampling
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U2 - 10.1080/01443615.2021.1953452
DO - 10.1080/01443615.2021.1953452
M3 - Article
AN - SCOPUS:85113589933
SN - 0144-3615
VL - 42
SP - 1255
EP - 1260
JO - Journal of Obstetrics and Gynaecology
JF - Journal of Obstetrics and Gynaecology
IS - 5
ER -