Population biobanks: Organizational models and prospects of application in gene geography and personalized medicine

E. V. Balanovska, M. K. Zhabagin, A. T. Agdzhoyan, M. I. Chukhryaeva, N. V. Markina, O. A. Balaganskaya, R. A. Skhalyakho, Yu M. Yusupov, O. M. Utevska, Yu V. Bogunov, R. R. Asilguzhin, D. O. Dolinina, Zh A. Kagazezheva, L. D. Damba, Valery Zaporozhchenko, A. G. Romanov, Kh D. Dibirova, M. A. Kuznetsova, M. B. Lavryashina, E. A. Pocheshkhova & 1 others O. P. Balanovsky

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Population biobanks are collections of thoroughly annotated biological material stored for many years. Population biobanks are a valuable resource for both basic science and applied research and are essential for extensive analysis of gene pools. Population biobanks make it possible to carry out fundamental studies of the genetic structure of populations, explore their genetic processes, and reconstruct their genetic history. The importance of biobanks for applied research is no less significant: they are essential for development of personalized medicine and genetic ecological monitoring of populations and are in high demand in forensic science. Establishment of an efficient and representative biobank requires strict observance of the principles of sample selection in populations, protocols of DNA extraction, quality control, and storage and documentation of biological materials. We reviewed regional biobanks and presented the organizational model of population biobank establishment based on the Biobank of Indigenous Population of Northern Eurasia created under supervision of E.V. Balanovska and O.P. Balanovsky. The results obtained using the biobanks in transdisciplinary research and prospective applications for the purposes of genogeography, genomic medicine, and forensic science are presented.

Original languageEnglish
Pages (from-to)1227-1243
Number of pages17
JournalRussian Journal of Genetics
Volume52
Issue number12
DOIs
Publication statusPublished - Dec 1 2016

Fingerprint

Organizational Models
Precision Medicine
Geography
Population
Genes
Forensic Sciences
Research
Genetic Phenomena
Gene Pool
Genetic Structures
Population Groups
Quality Control
Documentation
History
Medicine
DNA

Keywords

  • biobank
  • DNA identification
  • forensic expertise
  • gene pool
  • genogeography
  • monitoring
  • Northern Eurasia
  • personalized medicine
  • population

ASJC Scopus subject areas

  • Genetics

Cite this

Balanovska, E. V., Zhabagin, M. K., Agdzhoyan, A. T., Chukhryaeva, M. I., Markina, N. V., Balaganskaya, O. A., ... Balanovsky, O. P. (2016). Population biobanks: Organizational models and prospects of application in gene geography and personalized medicine. Russian Journal of Genetics, 52(12), 1227-1243. https://doi.org/10.1134/S1022795416120024

Population biobanks : Organizational models and prospects of application in gene geography and personalized medicine. / Balanovska, E. V.; Zhabagin, M. K.; Agdzhoyan, A. T.; Chukhryaeva, M. I.; Markina, N. V.; Balaganskaya, O. A.; Skhalyakho, R. A.; Yusupov, Yu M.; Utevska, O. M.; Bogunov, Yu V.; Asilguzhin, R. R.; Dolinina, D. O.; Kagazezheva, Zh A.; Damba, L. D.; Zaporozhchenko, Valery; Romanov, A. G.; Dibirova, Kh D.; Kuznetsova, M. A.; Lavryashina, M. B.; Pocheshkhova, E. A.; Balanovsky, O. P.

In: Russian Journal of Genetics, Vol. 52, No. 12, 01.12.2016, p. 1227-1243.

Research output: Contribution to journalReview article

Balanovska, EV, Zhabagin, MK, Agdzhoyan, AT, Chukhryaeva, MI, Markina, NV, Balaganskaya, OA, Skhalyakho, RA, Yusupov, YM, Utevska, OM, Bogunov, YV, Asilguzhin, RR, Dolinina, DO, Kagazezheva, ZA, Damba, LD, Zaporozhchenko, V, Romanov, AG, Dibirova, KD, Kuznetsova, MA, Lavryashina, MB, Pocheshkhova, EA & Balanovsky, OP 2016, 'Population biobanks: Organizational models and prospects of application in gene geography and personalized medicine' Russian Journal of Genetics, vol. 52, no. 12, pp. 1227-1243. https://doi.org/10.1134/S1022795416120024
Balanovska, E. V. ; Zhabagin, M. K. ; Agdzhoyan, A. T. ; Chukhryaeva, M. I. ; Markina, N. V. ; Balaganskaya, O. A. ; Skhalyakho, R. A. ; Yusupov, Yu M. ; Utevska, O. M. ; Bogunov, Yu V. ; Asilguzhin, R. R. ; Dolinina, D. O. ; Kagazezheva, Zh A. ; Damba, L. D. ; Zaporozhchenko, Valery ; Romanov, A. G. ; Dibirova, Kh D. ; Kuznetsova, M. A. ; Lavryashina, M. B. ; Pocheshkhova, E. A. ; Balanovsky, O. P. / Population biobanks : Organizational models and prospects of application in gene geography and personalized medicine. In: Russian Journal of Genetics. 2016 ; Vol. 52, No. 12. pp. 1227-1243.
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