Porous structure and water state in cross-linked polymer and protein cryo-hydrogels

Irina N. Savina, Vladimir M. Gun'Ko, Vladimir V. Turov, Maria Dainiak, Gary J. Phillips, Igor Yu Galaev, Sergey V. Mikhalovsky

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

The porous structure and the state of the water are two main factors which define the vast applications of hydrogels in the life science arena. The structural characterisation and water state in hydrogels produced by the cryogelation of poly(hydroxyethyl methacrylate) and gelatine were undertaken using different techniques. Images obtained using confocal laser scanning and multiphoton microscopies were analysed using ImageJ/Fiji software to estimate the total porosity, specific surface area and pore size and wall thickness distribution functions of each of the hydrogels. The hydration properties and structural characteristics of the nanopore component of the polymer and protein hydrogels were analysed using DSC, 1H NMR spectroscopy and cryoporometry and modelled using the PM6 quantum chemical method. The hydrogels produced by cryogelation were shown to have a large macropore volume, high pore interconnectivity and small specific surface area. The main portion of water was shown to be attributable to bulk water located within macropores. The relative amounts of bound water in the hydrogels were demonstrated to be small (

Original languageEnglish
Pages (from-to)4276-4283
Number of pages8
JournalSoft Matter
Volume7
Issue number9
DOIs
Publication statusPublished - May 7 2011
Externally publishedYes

Fingerprint

Hydrogels
Polymers
proteins
Water
polymers
water
Proteins
porosity
Specific surface area
life sciences
Nanopores
hydration
Hydration
Nuclear magnetic resonance spectroscopy
Pore size
distribution functions
Distribution functions
Microscopic examination
microscopy
computer programs

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics

Cite this

Savina, I. N., Gun'Ko, V. M., Turov, V. V., Dainiak, M., Phillips, G. J., Galaev, I. Y., & Mikhalovsky, S. V. (2011). Porous structure and water state in cross-linked polymer and protein cryo-hydrogels. Soft Matter, 7(9), 4276-4283. https://doi.org/10.1039/c0sm01304h

Porous structure and water state in cross-linked polymer and protein cryo-hydrogels. / Savina, Irina N.; Gun'Ko, Vladimir M.; Turov, Vladimir V.; Dainiak, Maria; Phillips, Gary J.; Galaev, Igor Yu; Mikhalovsky, Sergey V.

In: Soft Matter, Vol. 7, No. 9, 07.05.2011, p. 4276-4283.

Research output: Contribution to journalArticle

Savina, IN, Gun'Ko, VM, Turov, VV, Dainiak, M, Phillips, GJ, Galaev, IY & Mikhalovsky, SV 2011, 'Porous structure and water state in cross-linked polymer and protein cryo-hydrogels', Soft Matter, vol. 7, no. 9, pp. 4276-4283. https://doi.org/10.1039/c0sm01304h
Savina IN, Gun'Ko VM, Turov VV, Dainiak M, Phillips GJ, Galaev IY et al. Porous structure and water state in cross-linked polymer and protein cryo-hydrogels. Soft Matter. 2011 May 7;7(9):4276-4283. https://doi.org/10.1039/c0sm01304h
Savina, Irina N. ; Gun'Ko, Vladimir M. ; Turov, Vladimir V. ; Dainiak, Maria ; Phillips, Gary J. ; Galaev, Igor Yu ; Mikhalovsky, Sergey V. / Porous structure and water state in cross-linked polymer and protein cryo-hydrogels. In: Soft Matter. 2011 ; Vol. 7, No. 9. pp. 4276-4283.
@article{15bbe646f447464c8bfc7f329f50bad1,
title = "Porous structure and water state in cross-linked polymer and protein cryo-hydrogels",
abstract = "The porous structure and the state of the water are two main factors which define the vast applications of hydrogels in the life science arena. The structural characterisation and water state in hydrogels produced by the cryogelation of poly(hydroxyethyl methacrylate) and gelatine were undertaken using different techniques. Images obtained using confocal laser scanning and multiphoton microscopies were analysed using ImageJ/Fiji software to estimate the total porosity, specific surface area and pore size and wall thickness distribution functions of each of the hydrogels. The hydration properties and structural characteristics of the nanopore component of the polymer and protein hydrogels were analysed using DSC, 1H NMR spectroscopy and cryoporometry and modelled using the PM6 quantum chemical method. The hydrogels produced by cryogelation were shown to have a large macropore volume, high pore interconnectivity and small specific surface area. The main portion of water was shown to be attributable to bulk water located within macropores. The relative amounts of bound water in the hydrogels were demonstrated to be small (",
author = "Savina, {Irina N.} and Gun'Ko, {Vladimir M.} and Turov, {Vladimir V.} and Maria Dainiak and Phillips, {Gary J.} and Galaev, {Igor Yu} and Mikhalovsky, {Sergey V.}",
year = "2011",
month = "5",
day = "7",
doi = "10.1039/c0sm01304h",
language = "English",
volume = "7",
pages = "4276--4283",
journal = "Soft Matter",
issn = "1744-683X",
publisher = "Royal Society of Chemistry",
number = "9",

}

TY - JOUR

T1 - Porous structure and water state in cross-linked polymer and protein cryo-hydrogels

AU - Savina, Irina N.

AU - Gun'Ko, Vladimir M.

AU - Turov, Vladimir V.

AU - Dainiak, Maria

AU - Phillips, Gary J.

AU - Galaev, Igor Yu

AU - Mikhalovsky, Sergey V.

PY - 2011/5/7

Y1 - 2011/5/7

N2 - The porous structure and the state of the water are two main factors which define the vast applications of hydrogels in the life science arena. The structural characterisation and water state in hydrogels produced by the cryogelation of poly(hydroxyethyl methacrylate) and gelatine were undertaken using different techniques. Images obtained using confocal laser scanning and multiphoton microscopies were analysed using ImageJ/Fiji software to estimate the total porosity, specific surface area and pore size and wall thickness distribution functions of each of the hydrogels. The hydration properties and structural characteristics of the nanopore component of the polymer and protein hydrogels were analysed using DSC, 1H NMR spectroscopy and cryoporometry and modelled using the PM6 quantum chemical method. The hydrogels produced by cryogelation were shown to have a large macropore volume, high pore interconnectivity and small specific surface area. The main portion of water was shown to be attributable to bulk water located within macropores. The relative amounts of bound water in the hydrogels were demonstrated to be small (

AB - The porous structure and the state of the water are two main factors which define the vast applications of hydrogels in the life science arena. The structural characterisation and water state in hydrogels produced by the cryogelation of poly(hydroxyethyl methacrylate) and gelatine were undertaken using different techniques. Images obtained using confocal laser scanning and multiphoton microscopies were analysed using ImageJ/Fiji software to estimate the total porosity, specific surface area and pore size and wall thickness distribution functions of each of the hydrogels. The hydration properties and structural characteristics of the nanopore component of the polymer and protein hydrogels were analysed using DSC, 1H NMR spectroscopy and cryoporometry and modelled using the PM6 quantum chemical method. The hydrogels produced by cryogelation were shown to have a large macropore volume, high pore interconnectivity and small specific surface area. The main portion of water was shown to be attributable to bulk water located within macropores. The relative amounts of bound water in the hydrogels were demonstrated to be small (

UR - http://www.scopus.com/inward/record.url?scp=79955032722&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79955032722&partnerID=8YFLogxK

U2 - 10.1039/c0sm01304h

DO - 10.1039/c0sm01304h

M3 - Article

VL - 7

SP - 4276

EP - 4283

JO - Soft Matter

JF - Soft Matter

SN - 1744-683X

IS - 9

ER -