The Innovative Manufacturing Initiative (IMI) in the UK over the past decade has promoted the agenda of employing manufacturing sector principles in the execution of construction projects. Manufacturing management is founded on a process flow concept of the production activity. A notable development from the IMI programme, in this regard is the development of a Generic Design and Construction Process Protocol (GDCPP), based on the Cooper stage gate approach to managing the development of a new product in the manufacturing sector. The rationale for deploying the process approach to managing construction derives from the potential for replicating the step-change productivity improvements that has attended manufacturing projects that resulted from the adoption of such techniques. The possible gains in efficiency present prospective advantages for the application of the process approach to managing construction projects. In this paper the authors present preliminary stages of a qualitative investigation into the potential for employing the process approach in managing construction projects for "Egnatia Odos S.A.", one of the largest construction companies in Greece. The investigation was based on data collected through semi-structured questionnaires delivered through interview sessions with Egnatia's representatives. The study employs the GDCPP developed specifically for construction to explore the current constraints and bottlenecks that would have to be addressed to enable the practical uptake of the process approach by Greek construction professionals. Some early indications from the investigation are briefly discussed to provide an insight into the potential benefits and drawbacks of GDCPP's implementation in Greece and more specifically to one of the largest construction projects currently under implementation, namely that of the 680 Km Egnatia highway.