Abstract
In previous work, using high performance liquid chromatography with diode-array ultraviolet-visible (UV) absorbance and mass spectrometric detection, we have reported the identifications of dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene from the supercritical pyrolysis of synthetic jet fuel S-8. In the present study, we describe a method that indicates that dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene are carcinogenic polycyclic aromatic hydrocarbons (PAH). To prove this assertion, we have studied the UV spectra of several pairs of PAH that differ in two carbons. In all cases, we have observed an increase of the p band location related to the increase of the carcinogenic activity of the heavier PAH. The natural extension of this work to the PAH pairs naphtho[2,3-e]pyrene/ dibenzo[b,ghi]perylene and benzo[a]pentaphene/ benzo[cd]naphtho[1,2,3-lm]perylene has led us to conclude that dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene are also carcinogenic. The prediction of the carcinogenicity of other PAH based on similar principles is the subject of ongoing research.
| Original language | English |
|---|---|
| Title of host publication | American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers |
| Publication status | Published - 2008 |
| Externally published | Yes |
| Event | 235th National Meeting of the American Chemical Society, ACS 2008 - New Orleans, LA, United States Duration: Apr 6 2008 → Apr 10 2008 |
Other
| Other | 235th National Meeting of the American Chemical Society, ACS 2008 |
|---|---|
| Country | United States |
| City | New Orleans, LA |
| Period | 4/6/08 → 4/10/08 |
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ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)
Cite this
Prediction of the carcinogenic activity of two large PAH produced from the supercritical pyrolysis of Synthetic Jet Fuel S-8. / Oña, Jorge O.; Wornat, Mary J.
American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers. 2008.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Prediction of the carcinogenic activity of two large PAH produced from the supercritical pyrolysis of Synthetic Jet Fuel S-8
AU - Oña, Jorge O.
AU - Wornat, Mary J.
PY - 2008
Y1 - 2008
N2 - In previous work, using high performance liquid chromatography with diode-array ultraviolet-visible (UV) absorbance and mass spectrometric detection, we have reported the identifications of dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene from the supercritical pyrolysis of synthetic jet fuel S-8. In the present study, we describe a method that indicates that dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene are carcinogenic polycyclic aromatic hydrocarbons (PAH). To prove this assertion, we have studied the UV spectra of several pairs of PAH that differ in two carbons. In all cases, we have observed an increase of the p band location related to the increase of the carcinogenic activity of the heavier PAH. The natural extension of this work to the PAH pairs naphtho[2,3-e]pyrene/ dibenzo[b,ghi]perylene and benzo[a]pentaphene/ benzo[cd]naphtho[1,2,3-lm]perylene has led us to conclude that dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene are also carcinogenic. The prediction of the carcinogenicity of other PAH based on similar principles is the subject of ongoing research.
AB - In previous work, using high performance liquid chromatography with diode-array ultraviolet-visible (UV) absorbance and mass spectrometric detection, we have reported the identifications of dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene from the supercritical pyrolysis of synthetic jet fuel S-8. In the present study, we describe a method that indicates that dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene are carcinogenic polycyclic aromatic hydrocarbons (PAH). To prove this assertion, we have studied the UV spectra of several pairs of PAH that differ in two carbons. In all cases, we have observed an increase of the p band location related to the increase of the carcinogenic activity of the heavier PAH. The natural extension of this work to the PAH pairs naphtho[2,3-e]pyrene/ dibenzo[b,ghi]perylene and benzo[a]pentaphene/ benzo[cd]naphtho[1,2,3-lm]perylene has led us to conclude that dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene are also carcinogenic. The prediction of the carcinogenicity of other PAH based on similar principles is the subject of ongoing research.
UR - http://www.scopus.com/inward/record.url?scp=77955591848&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77955591848&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:77955591848
SN - 9780841269859
BT - American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers
ER -