Prediction of the carcinogenic activity of two large PAH produced from the supercritical pyrolysis of Synthetic Jet Fuel S-8

Jorge O. Oña, Mary J. Wornat

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In previous work, using high performance liquid chromatography with diode-array ultraviolet-visible (UV) absorbance and mass spectrometric detection, we have reported the identifications of dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene from the supercritical pyrolysis of synthetic jet fuel S-8. In the present study, we describe a method that indicates that dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene are carcinogenic polycyclic aromatic hydrocarbons (PAH). To prove this assertion, we have studied the UV spectra of several pairs of PAH that differ in two carbons. In all cases, we have observed an increase of the p band location related to the increase of the carcinogenic activity of the heavier PAH. The natural extension of this work to the PAH pairs naphtho[2,3-e]pyrene/ dibenzo[b,ghi]perylene and benzo[a]pentaphene/ benzo[cd]naphtho[1,2,3-lm]perylene has led us to conclude that dibenzo[b,ghi]perylene and benzo[cd]naphtho[1,2,3-lm]perylene are also carcinogenic. The prediction of the carcinogenicity of other PAH based on similar principles is the subject of ongoing research.

Original languageEnglish
Title of host publicationAmerican Chemical Society - 235th National Meeting, Abstracts of Scientific Papers
Publication statusPublished - 2008
Externally publishedYes
Event235th National Meeting of the American Chemical Society, ACS 2008 - New Orleans, LA, United States
Duration: Apr 6 2008Apr 10 2008

Other

Other235th National Meeting of the American Chemical Society, ACS 2008
CountryUnited States
CityNew Orleans, LA
Period4/6/084/10/08

Fingerprint

Synthetic fuels
Perylene
Jet fuel
Polycyclic Aromatic Hydrocarbons
Polycyclic aromatic hydrocarbons
Pyrolysis
Pyrene
High performance liquid chromatography
Diodes
Carbon
S-8 fuel
1,12-benzoperylene

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Oña, J. O., & Wornat, M. J. (2008). Prediction of the carcinogenic activity of two large PAH produced from the supercritical pyrolysis of Synthetic Jet Fuel S-8. In American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers

Prediction of the carcinogenic activity of two large PAH produced from the supercritical pyrolysis of Synthetic Jet Fuel S-8. / Oña, Jorge O.; Wornat, Mary J.

American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers. 2008.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Oña, JO & Wornat, MJ 2008, Prediction of the carcinogenic activity of two large PAH produced from the supercritical pyrolysis of Synthetic Jet Fuel S-8. in American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers. 235th National Meeting of the American Chemical Society, ACS 2008, New Orleans, LA, United States, 4/6/08.
Oña JO, Wornat MJ. Prediction of the carcinogenic activity of two large PAH produced from the supercritical pyrolysis of Synthetic Jet Fuel S-8. In American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers. 2008
Oña, Jorge O. ; Wornat, Mary J. / Prediction of the carcinogenic activity of two large PAH produced from the supercritical pyrolysis of Synthetic Jet Fuel S-8. American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers. 2008.
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