Pregnancy outcomes in women with diabetes mellitus – the impact of diabetes type and treatment

Gauri Bapayeva, Sanja Terzic, Jelena Dotlic, Karligash Togyzbayeva, Ulzhan Bugibaeva, Madina Mustafinova, Assem Alisheva, Simone Garzon, Milan Terzic, Antonio Simone Laganà

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Introduction: It has been estimated that approximately 16% of pregnancies worldwide are affected by preexisting or gestational insulin-dependent (type 1) or independent (type 2) diabetes mellitus (DM). Diabetes mellitus in pregnancy remains a high-risk condition for both mother and child. This study aimed to investigate pregnancy outcomes regarding DM types. Material and methods: The study included 323 DM patients delivered for 6 years (2012–2017). General and obstetric history data and all complications throughout the pregnancy and the early neonatal period were noted. Based on DM type, women were divided into 4 groups: pre-pregnancy/pre-existing DM, insulin-dependent or independent, and gestational diabetes mellitus with or without insulin therapy. Results: The majority of women had pre-existing insulin-independent DM (type II 62%). Some types of pregnancy/maternal complications were registered in almost 85% of examined pregnancies. However, all babies were live born and mostly with good outcome (36.85% with early neonatal complications). Diabetes mellitus type could not predict the occurrence of neonatal complications (p = 0.342). Pre-existing insulin-dependent DM increased the risk for pregnancy complications (p = 0.031; OR = 1.656). Conclusions: Diabetes mellitus type has a limited impact on pregnancy outcomes and the occurrence of maternal and neonatal complications. With adequate therapy the pregnancy outcome can be good regardless of DM type.

Original languageEnglish
Pages (from-to)37-46
Number of pages10
JournalPrzeglad Menopauzalny
Volume21
Issue number1
DOIs
Publication statusPublished - 2022
Externally publishedYes

Keywords

  • diabetes mellitus type
  • maternal complications
  • pregnancy outcome

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Obstetrics and Gynaecology

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