Prenatalna dijagnoza lizencefalije

Translated title of the contribution: Prenatal diagnosis of lissencephaly: A case report

Nataša Cerovac, Milan Terzić, Milan Borković, Nevena Divac, Radan Stojanović, Milica Prostran

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction. Lissencephaly (“smooth brain”) forms a major group of brain malformations due to abnormal neuronal migration. It can cause severe intellectual and motor disability and epilepsy in children. The prenatal diagnosis of this malformation is rare. Case report. We presented a case of the prenatal diagnosis of lissencephaly. A 30-year old pregnant woman was reffered to the hospital at the week 35 of gestation for magnetic resonance imaging (MRI) after an ultrasound examination demonstrated fetal cerebral ventriculomegaly. Fetal MRI of the brain showed “smooth”, agyrya cortex. The female infant was born at term with birth weight of 2,500 g and Apgar score 8, showing global developmental delay. Postnatal ultrasound and MRI confirmed classical lissencephaly. She is now 8 years old and has spastic quadriparesis, mental retardation and epilepsy. Conclusion. Confirmation of the ultrasound diagnosis with MRI is desirable for the prenatal diagnosis of lissencephaly.

Translated title of the contributionPrenatal diagnosis of lissencephaly: A case report
Original languageBulgarian
Pages (from-to)77-82
Number of pages6
JournalVojnosanitetski Pregled
Volume73
Issue number1
DOIs
Publication statusPublished - Jan 1 2016
Externally publishedYes

Keywords

  • Fetal monitoring
  • Lissencephaly
  • Magnetic resonance imaging
  • Mental retardation
  • Ultrasonography

ASJC Scopus subject areas

  • Pharmacology (medical)

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  • Cite this

    Cerovac, N., Terzić, M., Borković, M., Divac, N., Stojanović, R., & Prostran, M. (2016). Prenatalna dijagnoza lizencefalije. Vojnosanitetski Pregled, 73(1), 77-82. https://doi.org/10.2298/VSP140806010C