Abstract
Introduction In spite of the advances of modern medicine, puerperal infection is still one of the leading causes of morbidity and mortality of women in postpartal period. Objective The aim of this study was to analyse the presence of microorganisms in the cervicovaginal region of women in labour, as well as the frequency of puerperal endometritis in order to determine optimal treatment for isolated microorganisms and to prevent postpartal endometritis. Methods In this study, all women who gave birth to a healthy child per vias naturalis during the past two years in a tertiary health institution, Institute of Gynaecology and Obstetrics, Clinical Centre of Serbia, were analysed. The investigation involved 6,391 women in labour. Cervicovaginal smear was taken from all patients before labour, on admission for delivery, and sent to microbiological analysis. Standard procedures of bacterial cultivation were used. For statistical analysis of the results, we used the statistical programme SPSS 15. Results A single microorganism was isolated from each smear of 612 women and in 52 patients two microorganisms were registered in the same smear. We identified 10 sorts of microorganisms, out of which Escherichia coli (in 43.8% of cases), and Ennterococcus spp. (in 27.9% of cases) were the most frequent ones. Due to the appropriate approach, there were no cases of puerperal endometritis registered. Reactivity tests showed that Escherichia coli was sensitive to trimethoprim-sulphamethoxazole, Ennterococcus spp. to macrolides and cephalosporines, while both types of microorganisms were sensitive to synthetic penicillins and fluoroquinolines. Conclusion The study results show that 10.9% of pregnant women have positive findings of the cervicovaginal smear and that infection prevention should be directed towards Escherichia coli and Enterococcus spp. by administration of the listed antibiotics.
| Original language | English |
|---|---|
| Pages (from-to) | 506-510 |
| Number of pages | 5 |
| Journal | Srpski Arhiv Za Celokupno Lekarstvo |
| Volume | 137 |
| Issue number | 9-10 |
| DOIs | |
| Publication status | Published - Dec 24 2009 |
| Externally published | Yes |
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Keywords
- Antibiotics
- Cervicovaginal flora
- Endometritis
- Puerperium
ASJC Scopus subject areas
- Medicine(all)
Cite this
Prevention of postpartal endometritis : Antibiotic of choice. / Jovanović, Nebojša; Terzić, Milan; Dotlić, Jelena; Aleksić, Svetlana.
In: Srpski Arhiv Za Celokupno Lekarstvo, Vol. 137, No. 9-10, 24.12.2009, p. 506-510.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevention of postpartal endometritis
T2 - Antibiotic of choice
AU - Jovanović, Nebojša
AU - Terzić, Milan
AU - Dotlić, Jelena
AU - Aleksić, Svetlana
PY - 2009/12/24
Y1 - 2009/12/24
N2 - Introduction In spite of the advances of modern medicine, puerperal infection is still one of the leading causes of morbidity and mortality of women in postpartal period. Objective The aim of this study was to analyse the presence of microorganisms in the cervicovaginal region of women in labour, as well as the frequency of puerperal endometritis in order to determine optimal treatment for isolated microorganisms and to prevent postpartal endometritis. Methods In this study, all women who gave birth to a healthy child per vias naturalis during the past two years in a tertiary health institution, Institute of Gynaecology and Obstetrics, Clinical Centre of Serbia, were analysed. The investigation involved 6,391 women in labour. Cervicovaginal smear was taken from all patients before labour, on admission for delivery, and sent to microbiological analysis. Standard procedures of bacterial cultivation were used. For statistical analysis of the results, we used the statistical programme SPSS 15. Results A single microorganism was isolated from each smear of 612 women and in 52 patients two microorganisms were registered in the same smear. We identified 10 sorts of microorganisms, out of which Escherichia coli (in 43.8% of cases), and Ennterococcus spp. (in 27.9% of cases) were the most frequent ones. Due to the appropriate approach, there were no cases of puerperal endometritis registered. Reactivity tests showed that Escherichia coli was sensitive to trimethoprim-sulphamethoxazole, Ennterococcus spp. to macrolides and cephalosporines, while both types of microorganisms were sensitive to synthetic penicillins and fluoroquinolines. Conclusion The study results show that 10.9% of pregnant women have positive findings of the cervicovaginal smear and that infection prevention should be directed towards Escherichia coli and Enterococcus spp. by administration of the listed antibiotics.
AB - Introduction In spite of the advances of modern medicine, puerperal infection is still one of the leading causes of morbidity and mortality of women in postpartal period. Objective The aim of this study was to analyse the presence of microorganisms in the cervicovaginal region of women in labour, as well as the frequency of puerperal endometritis in order to determine optimal treatment for isolated microorganisms and to prevent postpartal endometritis. Methods In this study, all women who gave birth to a healthy child per vias naturalis during the past two years in a tertiary health institution, Institute of Gynaecology and Obstetrics, Clinical Centre of Serbia, were analysed. The investigation involved 6,391 women in labour. Cervicovaginal smear was taken from all patients before labour, on admission for delivery, and sent to microbiological analysis. Standard procedures of bacterial cultivation were used. For statistical analysis of the results, we used the statistical programme SPSS 15. Results A single microorganism was isolated from each smear of 612 women and in 52 patients two microorganisms were registered in the same smear. We identified 10 sorts of microorganisms, out of which Escherichia coli (in 43.8% of cases), and Ennterococcus spp. (in 27.9% of cases) were the most frequent ones. Due to the appropriate approach, there were no cases of puerperal endometritis registered. Reactivity tests showed that Escherichia coli was sensitive to trimethoprim-sulphamethoxazole, Ennterococcus spp. to macrolides and cephalosporines, while both types of microorganisms were sensitive to synthetic penicillins and fluoroquinolines. Conclusion The study results show that 10.9% of pregnant women have positive findings of the cervicovaginal smear and that infection prevention should be directed towards Escherichia coli and Enterococcus spp. by administration of the listed antibiotics.
KW - Antibiotics
KW - Cervicovaginal flora
KW - Endometritis
KW - Puerperium
UR - http://www.scopus.com/inward/record.url?scp=72249121286&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=72249121286&partnerID=8YFLogxK
U2 - 10.2298/SARH0910506J
DO - 10.2298/SARH0910506J
M3 - Article
VL - 137
SP - 506
EP - 510
JO - Srpski Arhiv Za Celokupno Lekarstvo
JF - Srpski Arhiv Za Celokupno Lekarstvo
SN - 0370-8179
IS - 9-10
ER -