Quantitative evaluation of heart rate variability associated with autonomic nervous system dysfunction/blockade

A. Bezerianos, L. Cimponeriu, P. Polydoropoulos, D. Alexopoulos, T. Bountis

Research output: Contribution to journalReview article

Abstract

In this study we performed a quantitative evaluation of the Heart Rate Variability (HRV) associated with normals and in patients with Autonomous Nervous System (ANS) dysfunction of two different origins: diabetic neuropathy and pharmacologically induced ANS blockade (after atropine and propanolol administration). Simple time and frequency domain statistics were computed from the RR time series. Due to of the strong evidence of nonlinearity in the cardiovascular system, the linear approach was extended by computing the correlation dimension (CD) as an estimator of the complexity of the three categories of data. The potential discriminating character of CD was examined as well as the validity of this estimator. We found that in the case of drug induced ANS blockade CD was statistically significantly less than in the other cases (normal and pathological ANS blockade). However, analysis of surrogate applied on the three categories of patients failed to assign nonlinear properties as captured by CD, suggesting that linear correlation is also involved.

Original languageEnglish
Pages (from-to)369-372
Number of pages4
JournalComputers in Cardiology
Volume0
Issue number0
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Autonomic Nervous System
Neurology
Nervous System
Heart Rate
Cardiovascular system
Diabetic Neuropathies
Cardiovascular System
Atropine
Propranolol
Time series
Statistics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

Cite this

Bezerianos, A., Cimponeriu, L., Polydoropoulos, P., Alexopoulos, D., & Bountis, T. (1998). Quantitative evaluation of heart rate variability associated with autonomic nervous system dysfunction/blockade. Computers in Cardiology, 0(0), 369-372.

Quantitative evaluation of heart rate variability associated with autonomic nervous system dysfunction/blockade. / Bezerianos, A.; Cimponeriu, L.; Polydoropoulos, P.; Alexopoulos, D.; Bountis, T.

In: Computers in Cardiology, Vol. 0, No. 0, 1998, p. 369-372.

Research output: Contribution to journalReview article

Bezerianos, A, Cimponeriu, L, Polydoropoulos, P, Alexopoulos, D & Bountis, T 1998, 'Quantitative evaluation of heart rate variability associated with autonomic nervous system dysfunction/blockade', Computers in Cardiology, vol. 0, no. 0, pp. 369-372.
Bezerianos A, Cimponeriu L, Polydoropoulos P, Alexopoulos D, Bountis T. Quantitative evaluation of heart rate variability associated with autonomic nervous system dysfunction/blockade. Computers in Cardiology. 1998;0(0):369-372.
Bezerianos, A. ; Cimponeriu, L. ; Polydoropoulos, P. ; Alexopoulos, D. ; Bountis, T. / Quantitative evaluation of heart rate variability associated with autonomic nervous system dysfunction/blockade. In: Computers in Cardiology. 1998 ; Vol. 0, No. 0. pp. 369-372.
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