Ratiometric pH sensor based on fluorescent core–shell nanoparticles

Timur Sh Atabaev, Hong Ha Thi Vu, Yoon Hwae Hwang, Hyung Kook Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This paper describes the preparation of fluorescent core–shell composite nanoparticles (NPs) that enable ratiometric pH measurements in a biologically relevant pH-range. The core of the composite NPs, which was used as the reference, consisted of Y2O3:Eu3+, which exhibited strong red fluorescent emission. A pH-sensitive fluorescein isothiocyanate (FITC) dye was incorporated in the outer amorphous silica shell as a pH indicator. The outer silica shell layer with FITC exhibited excellent fluorescent responses to pH, while the relative fluorescence intensity of Y2O3:Eu3+ was independent of the pH. Spectral characterization of the composite NPs by photoluminescence spectroscopy revealed good pH sensitivity with no significant differences over a relatively long period of time.

Original languageEnglish
Pages (from-to)8313-8316
Number of pages4
JournalJournal of Nanoscience and Nanotechnology
Volume17
Issue number11
DOIs
Publication statusPublished - 2017
Externally publishedYes

Keywords

  • Core–Shell Structure
  • Fluorescent Nanoparticles
  • PH Detection
  • Ratiometric Sensor

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)
  • Condensed Matter Physics

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